H2BK20ac Polyclonal Antibody

货号：PA5-17821

规格：100 µL

价格：4880

产品类型：标签抗体

品牌：Thermo Fisher

抗原：Synthetic acetylated peptide corresponding to sequ

物种：人/小鼠/大鼠

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	一抗	同型对照：
浓度：		用法：	1:200(ICC); 1:200(IF); 1:50(IHC(P));1:50(IP);1:1000(WB)

产品详细信息

It is not recommended to aliquot this antibody.This antibody is not cross-reactive with other acetylated histones.靶标信息

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The nucleosomes wrap further and compact DNA into chromotin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones play a central role in transciption regulation, DNA repair, DNA replication, and chromosomal stability. H2B has a broad antibacterial activity.

数据：

H2BK20ac Antibody (PA5-17821) in IFImmunofluorescent analysis of Acetyl-Histone H2B (Lys20) using a polyclonal antibody (Product # PA5-17821). H2BK20ac Antibody (PA5-17821) in IHC Immunohistochemical analysis of Acetyl-Histone H2B (Lys20) in paraffin-embedded human breast carcinoma using an Acetyl-Histone H2B (Lys20) polyclonal antibody (Product # PA5-17821) showing nuclear localization of histone H2B (left), or the same antibody preincubated with specific acetyl histone H2B peptide (right).

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技术参数

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