Human Flt-3 ELISA Kit ELISA试剂盒,Human Flt-3 ELISA Kit/人Flt-3 ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Human Flt-3 ELISA Kit ELISA试剂盒,Human Flt-3 ELISA Kit/人Flt-3 ELISA试剂盒

2024-10-23

Human Flt-3 ELISA Kit/人Flt-3 ELISA试剂盒

货号：EH197RB,EH197RBX5,EH197RBX10

规格：96 tests,5X96 tests,10X96 tests

价格：6641,29884,57271

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：人

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	0.24 ng/mL
检测范围	0.246-60 ng/mL
样本类型/体积	血清 50 μL 血浆 50 μL 上清液 50 μL
操作时间	1 hr 20 min
测试时间	4 hr 45 min
Homogenous (no wash)	No
批间变异系数（CV）	<12%
批内变异系数（CV）	<10%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	5 x 96 Tests
组份	- 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	FLT3 (CD135)
Protein aliases	CD135, CD135 antigen, fetal liver kinase 2, Fetal liver kinase-2, FL cytokine receptor, FLK-2, FLT-3, Fms-like tyrosine kinase 3, fms-related tyrosine kinase 3, growth factor receptor tyrosine kinase type III, Receptor-type tyrosine-protein kinase FLT3, Stem cell tyrosine kinase 1, STK-1
物种（Tested）	人
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	CD135, FLK-2, FLK2, FLT3, STK1
Gene ID	(Human) 2322
Gene symbol	FLT3
UniProt ID	(Human) P36888

Human Flt-3 quantitates human Flt-3 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Flt-3.Target information 靶标信息This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. The receptor consists of an extracellular domain composed of five immunoglobulin-like domains, one transmembrane region, and a cytoplasmic kinase domain split into two parts by a kinase-insert domain. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.该基因编码调节造血作用的III类受体酪氨酸激酶。该受体由细胞外结构域组成，该细胞外结构域由五个免疫球蛋白样结构域，一个跨膜区域和被激酶插入结构域分为两部分的胞质激酶结构域组成。受体通过与fms相关的酪氨酸激酶3配体与细胞外结构域的结合而被激活，从而诱导质膜中同二聚体的形成，从而导致受体的自身磷酸化。活化的受体激酶随后磷酸化并活化涉及骨髓中造血细胞凋亡，增殖和分化的途径中的多个细胞质效应分子。导致该受体组成性激活的突变会导致急性髓细胞性白血病和急性淋巴细胞性白血病。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

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Human Flt-3 ELISA Kit ELISA试剂盒,Human Flt-3 ELISA Kit/人Flt-3 ELISA试剂盒

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