Human IDO ELISA Kit ELISA试剂盒,Human IDO ELISA Kit/人IDO ELISA试剂盒

2024-10-23

Human IDO ELISA Kit/人IDO ELISA试剂盒

货号:EH246RB,EH246RBX5,EH246RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.81 ng/mL

检测范围0.819-200 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameIDO
Protein aliasesIDO-1, indolamine 2, 3 dioxygenase, indole 2, 3-dioxygenase, Indoleamine 2, 3-dioxygenase 1, Indoleamine-pyrrole 2

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesIDO, IDO-1, IDO1, INDO
Gene ID(Human) 3620
Gene symbolIDO1
UniProt ID(Human) P14902
Human IDO quantitates human IDO in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human IDO.人IDO定量测定血清,血浆,上清液中的人IDO。 该检测试剂盒将专门识别天然和重组人IDO。Target information 靶标信息IDO1 is an intracellular heme-containing enzyme that catalyzes the oxidative cleavage of the indole ring of several important regulatory molecules like tryptophan, serotonin, and melatonin. By doing this, IDO1 initiates the production of biologically active metabolites, commonly referred to as kynurenines. IDO1 is widely expressed in a variety of human tissues as well as in macrophages and dendritic cells (DCs). In inflammation, interferons (IFNs) act on specific receptors to trigger IDO1 induction. The production of IFN-gamma and induction of IDO1 represent important antimicrobial mechanisms. Degradation and depletion of tryptophan by IDO1 inhibits the growth of viruses, bacteria and parasites. Furthermore, IDO1 plays a complex and crucial role in immunoregulation during infection, pregnancy, autoimmunity, transplantation, and neoplasia.IDO1是一种细胞内含血红素的酶,可催化色氨酸,5-羟色胺和褪黑激素等几种重要调节分子的吲哚环的氧化裂解。 通过这样做,IDO1启动了生物活性代谢物(通常称为犬尿氨酸)的生产。 IDO1在各种人体组织以及巨噬细胞和树突状细胞(DC)中广泛表达。 在炎症中,干扰素(IFN)作用于特定受体以触发IDO1诱导。 IFN-γ的产生和IDO1的诱导代表重要的抗菌机制。 IDO1对色氨酸的降解和消耗抑制了病毒,细菌和寄生虫的生长。 此外,IDO1在感染,妊娠,自身免疫,移植和瘤形成过程中的免疫调节中起着复杂而至关重要的作用For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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