Human IGF-1 ELISA Kit ELISA试剂盒,Human IGF-1 ELISA Kit/人IGF-1 ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Human IGF-1 ELISA Kit ELISA试剂盒,Human IGF-1 ELISA Kit/人IGF-1 ELISA试剂盒

2024-10-23

Human IGF-1 ELISA Kit/人IGF-1 ELISA试剂盒

货号：EH250RB,EH250RBX5,EH250RBX10

规格：96 tests,5X96 tests,10X96 tests

价格：6641,29884,57271

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：人

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	0.1 ng/mL
检测范围	0.1-30 ng/mL
样本类型/体积	血清 50 μL 血浆 50 μL 上清液 50 μL
操作时间	1 hr 20 min
测试时间	4 hr 45 min
Homogenous (no wash)	No
批间变异系数（CV）	<12%
批内变异系数（CV）	<10%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	5 x 96 Tests
组份	- 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	IGF1
Protein aliases	GF-I, insulin-like growth factor 1 (somatomedin C), Insulin-like growth factor I, insulin-like growth factor IB, Mechano growth factor, MGF, Somatomedin-C
物种（Tested）	人
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	IBP1, IGF-I, IGF1, IGFI, MGF
Gene ID	(Human) 3479
Gene symbol	IGF1
UniProt ID	(Human) P05019

Human IGF-1 quantitates human IGF-1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human IGF-1.人IGF-1定量检测血清，血浆，上清液中的人IGF-1。该检测试剂盒将专门识别天然和重组人IGF-1。Target information 靶标信息IGF1 (Insulin-like growth factor-1) is structurally and functionally related to insulin but has a much higher growth-promoting activity. A variety of cellular responses are induced by IGF1, including cell proliferation, differentiation, migration, and survival. Further, IGF1 is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types in muscle, bone, and cartilage tissue. IGF1 stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regards to enhancing glucose uptake. In circulation, IGFs are predominantly bound to binding proteins (IGFBPs) which prolong the half-life of the IGFs and play a role in delivering them to target tissues. IGF-I is known as one of the most potent activators of the AKT signaling pathway which is known to be a stimulator of proliferation and an inhibitor of programmed cell death. Moreover, mature human IGF-I is 100% homologous with bovine and porcine proteins. Low levels of IGF1 have been linked to Alzheimer's disease. IGF1 is processed from a precursor, bound by a specific receptor, and secreted. Defects in the IGF1 gene are a cause of insulin-like growth factor 1 deficiency and several transcript variants encoding different isoforms have been found.IGF1（胰岛素样生长因子-1）在结构和功能上与胰岛素有关，但具有更高的促生长活性。 IGF1诱导多种细胞应答，包括细胞增殖，分化，迁移和存活。此外，IGF1是一种多肽生长因子，可刺激肌肉，骨骼和软骨组织中多种细胞类型的增殖。 IGF1刺激大鼠骨骼来源的成骨细胞（PyMS）中的葡萄糖转运，并且在比胰岛素低得多的浓度下有效，不仅在糖原和DNA合成方面，而且在提高葡萄糖吸收方面。在循环中，IGF主要与结合蛋白（IGFBP）结合，IGFBP延长了IGF的半衰期，并在将其递送至靶组织中发挥作用。 IGF-1是已知的AKT信号传导途径中最有效的活化剂之一，已知它是增殖的刺激剂和程序性细胞死亡的抑制剂。而且，成熟的人IGF-1与牛和猪蛋白100％同源。低水平的IGF1与阿尔茨海默氏病有关。 IGF1由前体加工而成，并与特定受体结合并被分泌。 IGF1基因的缺陷是胰岛素样生长因子1缺乏的原因，已经发现了几种编码不同同工型的转录变体。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

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Human IGF-1 ELISA Kit ELISA试剂盒,Human IGF-1 ELISA Kit/人IGF-1 ELISA试剂盒

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