Human ITGA2 ELISA Kit ELISA试剂盒,Human ITGA2 ELISA Kit/人ITGA2 ELISA试剂盒

2024-10-23

Human ITGA2 ELISA Kit/人ITGA2 ELISA试剂盒

货号:EH281RB,EH281RBX5,EH281RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.1 ng/mL

检测范围0.102-25 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameCD49b (Integrin alpha 2)
Protein aliasesalpha 2 subunit of VLA-2 receptor, CD49 antigen-like family member B, CD49b, Collagen receptor, GPIa, human platelet alloantigen system 5, Integrin alpha-2, integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), platelet antigen Br, platelet glycoprotein GPIa, Platelet membrane glycoprotein Ia, very late activation protein 2 receptor, alpha-2 subunit, VLA-2 subunit alpha

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesBR, CD49B, GPIa, HPA-5, ITGA2, VLA-2, VLAA2
Gene ID(Human) 3673
Gene symbolITGA2
UniProt ID(Human) P17301
Human ITGA2 quantitates human ITGA2 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human ITGA2.人ITGA2定量检测血清,血浆,上清液中的人ITGA2。 该检测试剂盒将专门识别天然和重组人ITGA2。Target information 靶标信息CD49b (Integrin alpha 2, Integrin alpha 2 chain, VLA-2 alpha chain, HM alpha 2) is a member of the integrin family. It is a glycoprotein with molecular weight of 150 kD, and it complexes with CD29 (Integrin beta 1) to form the heterodimeric integrin VLA-2 (integrin alpha 2 beta 1, or GPIa/IIa) complex. VLA-2 is an extracellular receptor for laminin, collagen, and fibronectin, and interaction with its ligands results in the activation of intracellular signaling pathways. It has reported roles in VEGF-induced angiogenesis in vivo, as well as adhesion and lymphocyte activation. CD49b is expressed by NK cells, NK-T cells, monocytes, platelets, and epithelial cells. It is also expressed on adaptive immune cells such as T and B cells, specifically on a subset of CD4+ T cells in the spleen, on intraepithelial and lamina propria lymphocytes in the intestine, as well as on a population of peripheral CD4+ type 1 T regulatory (Tr1) cells that co-express LAG-3.CD49b(整联蛋白α2,整联蛋白α2链,VLA-2α链,HMα2)是整联蛋白家族的成员。它是一种分子量为150 kD的糖蛋白,可与CD29(整联蛋白β1)复合形成异二聚体整联蛋白VLA-2(整联蛋白α2β1或GPIa / IIa)复合物。 VLA-2是层粘连蛋白,胶原蛋白和纤连蛋白的细胞外受体,与其配体的相互作用导致细胞内信号通路的激活。它已经报道了在体内VEGF诱导的血管生成以及粘附和淋巴细胞活化中的作用。 CD49b由NK细胞,NK-T细胞,单核细胞,血小板和上皮细胞表达。它还在适应性免疫细胞(例如T和B细胞)上表达,特别是在脾脏CD4 + T细胞的子集,肠上皮内和固有层淋巴细胞以及外周CD4 + 1T调节型人群中表达(Tr1)细胞共表达LAG-3。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

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