组蛋白乙酰化,多克隆抗体,Phospho-p300 (Ser1834) Polyclonal Antibody

2024-10-23

Phospho-p300 (Ser1834) Polyclonal Antibody

货号:PA5-64531

规格:100 µL

价格:5956

产品类型:标签抗体

品牌:Thermo Fisher

抗原:A synthesized peptide derived from human E1A-assoc

物种:人/小鼠/大鼠

宿主:兔

抗体亚型:IgG

荧光染料:其它

类型:一抗同型对照:
浓度: 1 mg/mL用法:1:1000(WB)
产品详细信息Phospho-p300 (Ser1834) Polyclonal Antibody detects endogenous levels of p300 only when phosphorylated at Ser1834. 靶标信息EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CPB (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CPB can stimulate transcription through activation of CREB. This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.
数据:

Phospho-p300 (Ser1834) Antibody (PA5-64531) in WB Western blot analysis of p300 in PMA treated HeLa whole cell lysates using a Phospho-p300 (Ser1834) Polyclonal Antibody (Product # PA5-64531).
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