Human LMP7/PSMB8 ELISA Kit ELISA试剂盒,Human LMP7/PSMB8 ELISA Kit/人LMP7 / PSMB8 ELISA试剂盒

2024-10-23

Human LMP7/PSMB8 ELISA Kit/人LMP7 / PSMB8 ELISA试剂盒

货号:EH303RB,EH303RBX5,EH303RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,27643,54564

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

2.2 ng/mL

检测范围2.2-500 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein namePSMB8
Protein aliasesLow molecular mass protein 7, low molecular weight protein 7, Macropain subunit C13, Multicatalytic endopeptidase complex subunit C13, protease component C13, proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7), proteasome catalytic subunit 3i, Proteasome component C13, proteasome subunit beta 5i, Proteasome subunit beta type-8, Proteasome subunit beta-5i, proteasome subunit Y2, proteasome-related gene 7, Really interesting new gene 10 protein

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesALDD, D6S216, D6S216E, JMP, LMP7, NKJO, PSMB5i, PSMB8, RING10, Y2
Gene ID(Human) 5696
Gene symbolPSMB8
UniProt ID(Human) P28062
Human LMP7/PSMB8 quantitates human LMP7/PSMB8 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human LMP7/PSMB8.人LMP7 / PSMB8定量检测血清,血浆,上清液中的人LMP7 / PSMB8。 该检测试剂盒专门识别天然和重组人LMP7 / PSMB8。Target information 靶标信息The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified; both isoforms are processed to yield the same mature subunit.蛋白酶体是具有高度有序的环状20S核心结构的多催化蛋白酶复合物。核心结构由4个环组成,由28个不同的亚基组成。 2个环由7个α亚基组成,2个环由7个β亚基组成。蛋白酶体以高浓度分布在整个真核细胞中,并以非溶酶体途径以ATP /泛素依赖性过程裂解肽。修饰的蛋白酶体(免疫蛋白酶体)的基本功能是加工I类MHC肽。该基因编码蛋白酶体B型家族(也称为T1B家族)的成员,该成员是20S核心β亚基。该基因位于MHC(主要组织相容性复合体)的II类区域。该基因的表达由γ干扰素诱导,并且该基因产物替代了免疫蛋白酶体中的催化亚基3(蛋白酶体β5亚基)。需要蛋白水解处理以产生成熟的亚基。已经鉴定出编码两个同工型的两个替代转录物;两种同工型都经过加工以产生相同的成熟亚基。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

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