VRK1 Polyclonal Antibody

货号：PA5-81887

规格：100 µL

价格：6049

产品类型：标签抗体

品牌：Thermo Fisher

抗原：Recombinant protein corresponding to Human VRK1

物种：人/小鼠

宿主：驴

抗体亚型：IgG

荧光染料：Alexa Fluor 488

类型:	一抗	同型对照：
浓度：	0.1 mg/mL	用法：	0.25-2 µg/mL(ICC);0.25-2 µg/mL(IF)；1:50-1:200（IHC(P)）0.04-0.4 µg/mL(WB)

产品详细信息Immunogen sequence: KAAQAGRQSS AKRHLAEQFA VGEIITDMAK KEWKVGLPIG QGGFGCIYLA DMNSSESVGS DAPCVVKVEP SDNGPLFTEL KFYQRAAKPE QIQKWIRTRK LKYLGVPKYW GSGLHDKNGK SYRFMIMDRF GSDLQKI 靶标信息Human vaccinia-related kinase 1 (VRK1) is a new kinase related to a poxvirus kinase, and more distantly to the casein kinase 1 family. VRK1 shows strong autophosphorylating activity in several Ser and Thr residues. VRK has also been found to be an upstream regulator of p53 that belongs to a new signaling pathway.

数据：

VRK1 Antibody (PA5-81887) in IF Immunofluorescent analysis of VRK1 in U-251 MG cells using a VRK1 polyclonal antibody (Product # PA5-81887). The analysis shows localization to nucleoplasm. Knockdown This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.VRK1 Antibody (PA5-81887)Antibody specificity was demonstrated by siRNA mediated knockdown of target protein. Rh30 were transfected with, control siRNA, VRK1 siRNA (probe #1), and VRK1 siRNA (probe #2) and a decrease in signal intensity was observed in Western Blot application using anti-VRK1 Polyclonal Antibody (Product # PA5-81887) used at a dilution of 0.4 µg/ml. Anti-PPIB was used as a loading control. Knockdown validation info.

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技术参数

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