组蛋白甲基化修饰,H3K4,,KMT2C Polyclonal Antibody

2024-10-24

KMT2C Polyclonal Antibody

货号:PA5-67359

规格:100 µL

价格:6049

产品类型:标签抗体

品牌:Thermo Fisher

抗原:Recombinant Human KMT2C

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:其它

类型:一抗同型对照:
浓度: 0.2 mg/mL用法:0.25-2 µg/mL(ICC);0.25-2 µg/mL(IF)
产品详细信息Immunogen sequence: TPPTMSQPTFP MVPQQLQHQQ HTTVISGHTS PVRMPSLPGW QPNSAPAHLP LNPPRIQPPI AQLPIKTCTP APGTVSNANP QHighest antigen sequence identity to the following orthologs - mouse 88%, rat 33%. 靶标信息Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. KMT2C/MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder.
数据:

KMT2C Antibody (PA5-67359) in IFImmunofluorescent staining of KMT2C in human cell line U-2 OS shows localization to nucleoplasm. Samples were probed using a KMT2C Polyclonal Antibody (Product # PA5-67359).
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