Human ROBO3 ELISA Kit ELISA试剂盒,Human ROBO3 ELISA /人ROBO3 ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Human ROBO3 ELISA Kit ELISA试剂盒,Human ROBO3 ELISA /人ROBO3 ELISA试剂盒

2024-10-24

Human ROBO3 ELISA /人ROBO3 ELISA试剂盒

货号：EH393RB,EH393RBX5,EH393RBX10

规格：96 tests,5X96 tests,10X96 tests

价格：6641,28472,57271

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：人

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	0.06 ng/mL
检测范围	15-0.06 ng/mL
样本类型/体积	血清 50 μL 血浆 50 μL 上清液 50 μL
操作时间	1 hr 20 min
测试时间	4 hr 45 min
Homogenous (no wash)	No
批间变异系数（CV）	<12%
批内变异系数（CV）	<10%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	5 x 96 Tests
组份	- 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	ROBO3
Protein aliases	retinoblastoma inhibiting gene 1, Roundabout homolog 3, roundabout, axon guidance receptor, homolog 3, Roundabout-like protein 3
物种（Tested）	人
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	HGPPS, HGPS, RBIG1, RIG1, ROBO3
Gene ID	(Human) 64221
Gene symbol	ROBO3
UniProt ID	(Human) Q96MS0

Human ROBO3 quantitates human ROBO3 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human ROBO3.人ROBO3定量检测血清，血浆，上清液中的人ROBO3。该检测试剂盒将专门识别天然和重组人ROBO3。Target information 靶标信息This gene is a member of the Roundabout (ROBO) gene family that controls neurite outgrowth, growth cone guidance, and axon fasciculation. ROBO proteins are a subfamily of the immunoglobulin transmembrane receptor superfamily. SLIT proteins 1-3, a family of secreted chemorepellants, are ligands for ROBO proteins and SLIT/ROBO interactions regulate myogenesis, leukocyte migration, kidney morphogenesis, angiogenesis, and vasculogenesis in addition to neurogenesis. This gene, ROBO3, has a putative extracellular domain with five immunoglobulin (Ig)-like loops and three fibronectin (Fn) type III motifs, a transmembrane segment, and a cytoplasmic tail with three conserved signaling motifs: CC0, CC2, and CC3 (CC for conserved cytoplasmic). Unlike other ROBO family members, ROBO3 lacks motif CC1. The ROBO3 gene regulates axonal navigation at the ventral midline of the neural tube. In mouse, loss of Robo3 results in a complete failure of commissural axons to cross the midline throughout the spinal cord and the hindbrain. Mutations ROBO3 result in horizontal gaze palsy with progressive scoliosis (HGPPS); an autosomal recessive disorder characterized by congenital absence of horizontal gaze, progressive scoliosis, and failure of the corticospinal and somatosensory axon tracts to cross the midline in the medulla.该基因是回旋（ROBO）基因家族的成员，该家族控制神经突的生长，生长锥的引导和轴突的束缚。 ROBO蛋白是免疫球蛋白跨膜受体超家族的一个亚家族。 SLIT蛋白1-3是一种分泌的化学趋化剂，是ROBO蛋白的配体，除神经发生外，SLIT / ROBO相互作用还调节肌生成，白细胞迁移，肾脏形态发生，血管生成和血管生成。该基因ROBO3具有一个推测的细胞外结构域，带有五个免疫球蛋白（Ig）样环和三个纤连蛋白（Fn）III型基序，一个跨膜区段以及一个带有三个保守信号基序的胞质尾巴：CC0，CC2和CC3（ CC代表保守的细胞质）。与其他ROBO家族成员不同，ROBO3缺少主题CC1。 ROBO3基因调节神经管腹中线的轴突导航。在小鼠中，Robo3的缺失导致连合轴突完全横穿整个脊髓和后脑的中线。 ROBO3突变导致水平视线麻痹伴进行性脊柱侧凸（HGPPS）；一种常染色体隐性遗传疾病，其特征是先天性水平视线缺失，进行性脊柱侧弯以及皮质脊髓和躯体感觉轴突束无法穿过延髓中线。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

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Human ROBO3 ELISA Kit ELISA试剂盒,Human ROBO3 ELISA /人ROBO3 ELISA试剂盒

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