Human SIGIRR ELISA Kit ELISA试剂盒,Human SIGIRR ELISA Kit/人SIGIRR ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Human SIGIRR ELISA Kit ELISA试剂盒,Human SIGIRR ELISA Kit/人SIGIRR ELISA试剂盒

2024-10-24

Human SIGIRR ELISA Kit/人SIGIRR ELISA试剂盒

货号：EH422RB,EH422RBX5,EH422RBX10

规格：96 tests,5X96 tests,10X96 tests

价格：6641,29887,57271

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：人

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	2 ng/mL
检测范围	2-500 ng/mL
样本类型/体积	血清 50 μL 血浆 50 μL 上清液 50 μL
操作时间	1 hr 20 min
测试时间	4 hr 45 min
Homogenous (no wash)	No
批间变异系数（CV）	<12%
批内变异系数（CV）	<10%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	5 x 96 Tests
组份	- 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	SIGIRR
Protein aliases	Single Ig IL-1-related receptor, Single Ig IL-1R-related molecule, single immunoglobulin and toll-interleukin 1 receptor (TIR) domain, single immunoglobulin domain IL1R1 related, Single immunoglobulin domain-containing IL1R-related protein, TIR8, Toll/interleukin-1 receptor 8
物种（Tested）	人
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	IL-1R8, SIGIRR, TIR8, UNQ301/PRO342
Gene ID	(Human) 59307
Gene symbol	SIGIRR
UniProt ID	(Human) Q6IA17

Human SIGIRR quantitates human SIGIRR in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human SIGIRR.人SIGIRR定量测定血清，血浆，上清液中的人SIGIRR。该检测试剂盒将只识别天然和重组人SIGIRR。Target information 靶标信息SIGIRR (single Ig IL-1R-related molecule) is a novel member of the interleukin 1 receptor (IL-1R) superfamily. Although it shows the typical conserved motifs that characterize the IL-1R and Toll superfamily, it is structurally and functionally distinct from both. SIGIRR has only one Ig domain in its extracellular portion whereas the IL-1R family contains three Ig folds. An unusually long cytoplasmic domain is reminiscent of the structure of drosophila Toll, yet the SIGIRR peptide sequence is more closely related to IL-1RI. A chimera, in which the SIGIRR intracellular domain was fused to the IL-1R extracellular domain, did not activate NFkappaB unlike similar fusion proteins of other IL-1R related molecules. Phylogenetic data that suggest that the plasma membrane protein SIGIRR is a close functional relative of MyD88 in mammals.SIGIRR（单个Ig IL-1R相关分子）是白介素1受体（IL-1R）超家族的新成员。尽管显示了IL-1R和Toll超家族的典型保守基序，但在结构和功能上均与之不同。 SIGIRR在其细胞外部分仅具有一个Ig结构域，而IL-1R家族包含3个Ig折叠。一个异常长的胞质结构域使人联想起果蝇Toll的结构，但SIGIRR肽序列与IL-1RI更紧密相关。嵌合体，其中SIGIRR细胞内结构域与IL-1R细胞外结构域融合，不激活NFkappaB，这与其他IL-1R相关分子的相似融合蛋白不同。系统发育数据表明，质膜蛋白SIGIRR是MyD88在哺乳动物中的近亲。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

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Human SIGIRR ELISA Kit ELISA试剂盒,Human SIGIRR ELISA Kit/人SIGIRR ELISA试剂盒

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