Human Siglec-3 ELISA Kit ELISA试剂盒,Human Siglec-3 ELISA Kit/人Siglec-3 ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Human Siglec-3 ELISA Kit ELISA试剂盒,Human Siglec-3 ELISA Kit/人Siglec-3 ELISA试剂盒

2024-10-24

Human Siglec-3 ELISA Kit/人Siglec-3 ELISA试剂盒

货号：EH423RB,EH423RBX5,EH423RBX10

规格：96 tests,5X96 tests,10X96 tests

价格：6641,29884,57271

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：人

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	1.5 ng/mL
检测范围	1.5-50 ng/mL
样本类型/体积	血清 50 μL 血浆 50 μL 上清液 50 μL
操作时间	1 hr 20 min
测试时间	4 hr 45 min
Homogenous (no wash)	No
批间变异系数（CV）	<12%
批内变异系数（CV）	<10%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	5 x 96 Tests
组份	- 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	CD33
Protein aliases	CD33, CD33 antigen (gp67), CD33 molecule transcript, gp67, Myeloid cell surface antigen CD33, sialic acid binding Ig-like lectin 3, Sialic acid-binding Ig-like lectin 3, Siglec-3
物种（Tested）	人
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	CD33, p67, SIGLEC-3, SIGLEC3
Gene ID	(Human) 945
Gene symbol	CD33
UniProt ID	(Human) P20138

Human Siglec-3 quantitates human Siglec-3 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Siglec-3.人Siglec-3定量分析血清，血浆，上清液中的人Siglec-3。该检测试剂盒将专门识别天然和重组人Siglec-3。Target information 靶标信息CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies, and these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. Further, CD33 is found on granulocyte and macrophage precursors in the bone marrow, but is not on pluripotent stem cells. CD33 is also expressed on, and is a useful marker for, peripheral monocytes. CD33 is useful for distinguishing myelogenous leukemia cells from lymphoid or erythroid leukemias. Diseases associated with CD43 dysfunction include gallbladder lymphoma and extracutaneous mastocytoma.CD33是唾液酸结合免疫球蛋白样凝集素（Siglec）家族的跨膜蛋白。能够吸收蛋白酪氨酸磷酸酶SHP-1和SHP-2发出信号的基于免疫受体酪氨酸的抑制性基序（ITIM）分子，这些ITIM也用于泛素介导的细胞受体的去除。 CD33在骨髓单核细胞谱系的细胞上表达，与细胞表面N-和O-聚糖中的唾液酸残基结合，是急性髓细胞性白血病的治疗靶标。此外，在骨髓中的粒细胞和巨噬细胞前体上发现了CD33，但在多能干细胞上却没有。 CD33还在外周单核细胞上表达，并且是其有用的标记。 CD33可用于区分骨髓性白血病细胞与淋巴样或红系白血病。与CD43功能障碍有关的疾病包括胆囊淋巴瘤和皮外肥大细胞瘤。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

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Human Siglec-3 ELISA Kit ELISA试剂盒,Human Siglec-3 ELISA Kit/人Siglec-3 ELISA试剂盒

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