Human Siglec-7 ELISA Kit ELISA试剂盒,Human Siglec-7 ELISA Kit/人Siglec-7 ELISA试剂盒

2024-10-24

Human Siglec-7 ELISA Kit/人Siglec-7 ELISA试剂盒

货号:EH425RB,EH425RBX5,EH425RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.1 ng/mL

检测范围0.1-25 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameSIGLEC7
Protein aliasesAdhesion inhibitory receptor molecule 1, adhesion inhibitory receptor molecule 1, siglec-7, AIRM-1, CD328, CDw328, D-siglec, p75, QA79 membrane protein, sialic acid binding Ig-like lectin 7, sialic acid binding immunoglobulin-like lectin 7, Sialic acid-binding Ig-like lectin 7, Siglec-7

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesAIRM1, CD328, CDw328, D-siglec, p75, p75/AIRM1, QA79, SIGLEC-7, SIGLEC19P, SIGLEC7, SIGLECP2
Gene ID(Human) 27036
Gene symbolSIGLEC7
UniProt ID(Human) Q9Y286
Human Siglec-7 quantitates human Siglec-7 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Siglec-7.人Siglec-7定量测定血清,血浆,上清液中的人Siglec-7。 该检测试剂盒将专门识别天然和重组人Siglec-7。Target information 靶标信息Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).介导唾液酸依赖性细胞结合的推定粘附分子。 优选结合α-2,3-和α-2,6-连接的唾液酸。 还结合二唾液酸神经节苷脂(二唾液酸乳糖基糖苷,二唾液酸乳糖四糖神经酰胺和二唾液酸GalNAc乳糖四糖神经酰胺)。 唾液酸识别位点可以被与同一细胞表面上的唾液酸的顺式相互作用所掩盖。 在免疫应答中,可通过其SH2结构域募集细胞质磷酸酶来抑制配体诱导的酪氨酸磷酸化,这些SH2结构域通过信号分子的去磷酸化来阻断信号传导。 介导抑制自然杀伤细胞的细胞毒性。 可能在造血中起作用。 抑制CD34 +细胞前体向骨髓单核细胞谱系的分化和白血病髓样细胞的增殖(体外)。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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