Human SIRT1 ELISA Kit ELISA试剂盒,Human SIRT1 ELISA Kit/人SIRT1 ELISA试剂盒

2024-10-24

Human SIRT1 ELISA Kit/人SIRT1 ELISA试剂盒

货号:EH427RB,EH427RBX5,EH427RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

1.23 ng/mL

检测范围1.23-300 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameSIRT1
Protein aliases75SirT1, hSIR2, hSIRT1, NAD-dependent protein deacetylase sirtuin-1, Regulatory protein SIR2 homolog 1, SIR2-like protein 1, SirtT1 75 kDa fragment, sirtuin type 1

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesSIR2, SIR2alpha, SIR2L1, SIRT1
Gene ID(Human) 23411
Gene symbolSIRT1
UniProt ID(Human) Q96EB6
Human SIRT1 quantitates human SIRT1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human SIRT1.人SIRT1定量检测血清,血浆,上清液中的人SIRT1。 该检测试剂盒将专门识别天然和重组人SIRT1。Target information 靶标信息NAD-dependent protein deacetylase sirtuin-1 (SIRT1) links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, repsonse to DNA damage, metabolism, apoptosis, and autophagy. SIRT1 can modulate chromatin function through deacetylation of histones and can promote alterations in the methylation of histone and DNA, leading to transcriptional repression. It is essential in skeletal muscle cell differentiation and in response to low nutrients mediates the inhibitory effect on skeletal myoblast differentiation which also involves 5'-AMP-activated protein kinase (AMPK) and nicotinamide phosphoribosyltransferase (NAMPT).NAD依赖性蛋白脱乙酰酶sirtuin-1(SIRT1)将转录调控直接与细胞内能量相关联,并参与多种分离的细胞功能的协调,例如细胞周期,对DNA损伤的应答,代谢,细胞凋亡和自噬。 SIRT1可以通过组蛋白的去乙酰化来调节染色质的功能,并可以促进组蛋白和DNA的甲基化改变,从而导致转录抑制。 它在骨骼肌细胞分化中必不可少,对低营养物质的反应介导对骨骼肌成肌细胞分化的抑制作用,其中还涉及5'-AMP激活的蛋白激酶(AMPK)和烟酰胺磷酸核糖基转移酶(NAMPT)。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

技术参数
© bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪是专业的授权总代理区域代理经销平台。
© 如需询价,请加客服QQ:1749072012 、客服微信:jinshanbio,或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务,数据资源基于CC协议。
© 本文地址:https://gibcohyclone.cn/thread-46859.htm
产品询价需求提交
返回
扫码添加客服微信,咨询产品报价