Human ULBP-1 ELISA Kit ELISA试剂盒,Human ULBP-1 ELISA Kit/人ULBP-1 ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Human ULBP-1 ELISA Kit ELISA试剂盒,Human ULBP-1 ELISA Kit/人ULBP-1 ELISA试剂盒

2024-10-24

Human ULBP-1 ELISA Kit/人ULBP-1 ELISA试剂盒

货号：EH476RB,EH476RBX5,EH476RBX10

规格：96 tests,5X96 tests,10X96 tests

价格：6641,29884,57271

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：人

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	0.4 ng/mL
检测范围	0.4-100 ng/mL
样本类型/体积	血清 50 μL 血浆 50 μL 上清液 50 μL
操作时间	1 hr 20 min
测试时间	4 hr 45 min
Homogenous (no wash)	No
批间变异系数（CV）	<12%
批内变异系数（CV）	<10%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	5 x 96 Tests
组份	- 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	ULBP1
Protein aliases	ALCAN-beta, N2DL-1, NKG2D ligand 1, Retinoic acid early transcript 1I, UL16-binding protein 1
物种（Tested）	人
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	N2DL-1, N2DL1, NKG2DL1, RAET1I, ULBP1
Gene ID	(Human) 80329
Gene symbol	ULBP1
UniProt ID	(Human) Q9BZM6

Human ULBP-1 quantitates human ULBP-1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human ULBP-1.人ULBP-1定量检测血清，血浆，上清液中的人ULBP-1。该检测试剂盒将专门识别天然和重组人ULBP-1。Target information 靶标信息ULBP1 is the ligand for the NKG2D receptor, together with at least ULBP2 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface.ULBP1与ULBP2和ULBP3一起是NKG2D受体的配体。 ULBP激活原代NK细胞中的多个信号通路，从而导致细胞因子和趋化因子的产生。 ULBPs配体与NKG2D的结合诱导钙动员并激活JAK2，STAT5，ERK和PI3K激酶/ Akt信号转导途径。在CMV感染的细胞中，与可溶性CMV糖蛋白UL16相互作用。与UL16的相互作用阻止了与NKG2D受体的相互作用，从而提供了一种机制，CMV感染的细胞可以通过该机制逃避免疫系统。 UL16还使ULBP1保留在ER和顺式高尔基体中，因此不会到达细胞表面。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

技术参数

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Human ULBP-1 ELISA Kit ELISA试剂盒,Human ULBP-1 ELISA Kit/人ULBP-1 ELISA试剂盒

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