Human UCH-L1/PGP9.5 ELISA Kit ELISA试剂盒,Human UCH-L1/PGP9.5 ELISA Kit/人UCH-L1/PGP9.5 ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Human UCH-L1/PGP9.5 ELISA Kit ELISA试剂盒,Human UCH-L1/PGP9.5 ELISA Kit/人UCH-L1/PGP9.5 ELISA试剂盒

2024-10-24

Human UCH-L1/PGP9.5 ELISA Kit/人UCH-L1/PGP9.5 ELISA试剂盒

货号：EH475RB,EH475RBX5,EH475RBX10

规格：96 tests,5X96 tests,10X96 tests

价格：6641,29884,57271

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：人

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	0.82 ng/mL
检测范围	0.82-200 ng/mL
样本类型/体积	血清 50 μL 血浆 50 μL 上清液 50 μL
操作时间	1 hr 20 min
测试时间	4 hr 45 min
Homogenous (no wash)	No
批间变异系数（CV）	<12%
批内变异系数（CV）	<10%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	5 x 96 Tests
组份	- 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	PGP9.5
Protein aliases	epididymis luminal protein 117, epididymis secretory protein Li 53, Neuron cytoplasmic protein 9.5, PGP 9.5, PGP9.5, ubiquitin C-terminal hydrolase, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), Ubiquitin carboxyl-terminal hydrolase isozyme L1, Ubiquitin thioesterase L1, ubiquitin thiolesterase, UCH-L1
物种（Tested）	人
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	HEL-117, HEL-S-53, NDGOA, PARK5, PGP 9.5, PGP9.5, PGP95, Uch-L1, UCHL1
Gene ID	(Human) 7345
Gene symbol	UCHL1
UniProt ID	(Human) P09936

Human UCH-L1/PGP9.5 quantitates human UCH-L1/PGP9.5 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human UCH-L1/PGP9.5.人UCH-L1 / PGP9.5定量检测血清，血浆，上清液中的人UCH-L1 / PGP9.5。该检测试剂盒将专门识别天然和重组人UCH-L1 / PGP9.5。Target information 靶标信息PGP9.5 (Protein gene product 9.5, UCH-L1, PARK5) is a neuron specific protein, structurally and immunologically distinct from neuron specific enolase. PGP9.5 has a molecular weight of 27 kDa and was first identified by high resolution two dimensional PAGE. PGP9.5 is a member of ubiquitin carboxyl-terminal hydrolase family 1 (peptidase family C12) with a ubiquitin carboxyl-terminal hydrolase domain. PGP9.5 is well known for having ubiquitin hydrolase and ligase activities that hydrolyzes small C-terminal adducts of ubiquitin to generate ubiquitin monomers. PGP9.5 is present in neurons and nerve fibers at all levels of the central and peripheral nervous system, in neuroendocrine cells, in segments of the renal tubules, in spermatogonia and Leydig cells of the testis, in ova and in some cells of both the pregnant and non-pregnant corpus luteum. Over expression of PGP9.5 leads to non-small cell lung cancer while decreased expression leads to Huntington disease and Alzheimer disease. Since PGP9.5 is present in cellular inclusions, it can be a useful as a neuronal marker and in the studies of neurodegenerative disorders such as with Parkinson disease.PGP9.5（蛋白质基因产物9.5，UCH-L1，PARK5）是一种神经元特异性蛋白，在结构和免疫学上不同于神经元特异性烯醇化酶。 PGP9.5的分子量为27 kDa，首先通过高分辨率二维PAGE鉴定。 PGP9.5是具有遍在蛋白羧基末端水解酶结构域的泛素羧基末端水解酶家族1（肽酶家族C12）的成员。 PGP9.5具有泛素水解酶和连接酶活性，可水解泛素的小C末端加合物生成泛素单体，因此广为人知。 PGP9.5存在于中枢神经系统和末梢神经系统各个水平的神经元和神经纤维中，神经内分泌细胞中，肾小管的各个部分中，睾丸的精原细胞和Leydig细胞中，卵中以及两者的一些细胞中。怀孕和未怀孕的黄体。 PGP9.5的过表达导致非小细胞肺癌，而表达降低则导致亨廷顿病和阿尔茨海默氏病。由于PGP9.5存在于细胞内含物中，因此可用作神经元标记和研究神经退行性疾病（如帕金森氏病）。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

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Human UCH-L1/PGP9.5 ELISA Kit ELISA试剂盒,Human UCH-L1/PGP9.5 ELISA Kit/人UCH-L1/PGP9.5 ELISA试剂盒

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