Human Vasohibin-1 ELISA Kit ELISA试剂盒,Human Vasohibin-1 ELISA Kit/人Vasohibin-1 ELISA试剂盒

2024-10-24

Human Vasohibin-1 ELISA Kit/人Vasohibin-1 ELISA试剂盒

货号:EH480RB,EH480RBX5,EH480RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,54564

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

11 pg/mL

检测范围11-2,500 pg/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameVASH1
Protein aliasesTTCP 1, Tubulin carboxypeptidase 1, Tubulinyl-Tyr carboxypeptidase 1, Tyrosine carboxypeptidase 1, Vasohibin-1

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesKIAA1036, VASH, VASH1
Gene ID(Human) 22846
Gene symbolVASH1
UniProt ID(Human) Q7L8A9
Human Vasohibin-1 quantitates human Vasohibin-1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Vasohibin-1.人Vasohibin-1定量测定血清,血浆,上清液中的人Vasohibin-1。该检测试剂盒专门识别天然和重组人Vasohibin-1。Target information 靶标信息VASH1 was originally identified as an endothelium-derived vascular endothelial growth factor (VEGF)-inducible angiogenesis inhibitor that acts in a negative feedback manner. VASH1 mRNA is expressed brain, heart, kidney and placenta in the adult, with robust expression in various organs during embryonic development. VASH1 expression in tumor cells and tumor vasculature is silenced by methylation by increased expression of Zeste homolog 2 (EZH2). The increase of EZH2 expression is induced by VEGF stimulation, leading to poor clinical prognosis. Recombinant adenovirus expressing VASH prevented tumor angiogenesis and inhibited tumor growth, suggesting that it may be a potentially valuable antitumor therapy in the clinic.VASH1最初被确定为以负反馈方式起作用的内皮源性血管内皮生长因子(VEGF)诱导的血管生成抑制剂。 VASH1 mRNA在成年人中可在大脑,心脏,肾脏和胎盘中表达,在胚胎发育过程中在各个器官中都有强大的表达。 肿瘤细胞和肿瘤脉管系统中VASH1的表达通过Zeste同源物2(EZH2)表达的增加而被甲基化沉默。 EZH2表达的增加是由VEGF刺激引起的,导致临床预后不良。 表达VASH的重组腺病毒可阻止肿瘤血管生成并抑制肿瘤生长,这表明它可能是临床上潜在的有价值的抗肿瘤治疗方法。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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