Rat anti mouse IgG HEAVY chain 伯乐 Rat anti mouse IgG HEAVY chain MCA424

2024-10-29

Rat anti mouse IgG HEAVY chain

货号:MCA424

规格:0.25 mg

市场价格:3018

产品类型:二抗

品牌:Bio-Rad

物种:小鼠

宿主:大鼠

抗体亚型:其它

克隆号:COCKTAIL

荧光染料:Purified

产品介绍
Mouse anti Human SQSTM1 antibody, clone 2C11recognizes human SQSTM1, also known as Sequestosome-1, p62 or EBIAP. SQSTM1 is a ~62kDa ubiquitously expressed molecule bearing an N-terminalOPRdomain which mediates homo-oligomerization and interactions with other proteins. SQSTM1 also bears a C-terminalUBAdomain, responsible for binding to poly-ubiquitinated substrates.SQSTM1 is involved in the autophagic degradation of poly-ubiquitinated proteins (Weiet al.2013) and in bone remodelling through activation of of osteoclasts. Mutations in the SQSTM1 gene have been implicated in Paget's disease of bone (Laurinet al.2002)Mouse anti human SQSTM1, clone 2C11 has been used successfully for the identification of SQSTM1 in Hela cells by western blotting.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationPurified IgG prepared by affinity chromatography on Protein A from ascites
Buffer SolutionPhosphate buffered saline
Preservative StabilisersNone present
ImmunogenRecombinant protein corresponding to aa 1 - 441 of human SQSTM1.
Approx. Protein ConcentrationsIg concentration 0.5 mg/ml
Fusion PartnersSpleen cells from BALB/c mice were fused with cells from the Sp2/0 myeloma cell line.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store at -20℃ only.Storage in frost-free freezers is not recommended.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.

技术参数

产品应用 ELISA

产品类型 Monoclonal Antibody

推荐用于 ELISA

© bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪是专业的授权总代理区域代理经销平台。
© 如需询价,请加客服QQ:1749072012 、客服微信:jinshanbio,或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务,数据资源基于CC协议。
© 本文地址:https://gibcohyclone.cn/thread-52202.htm
产品询价需求提交
返回
扫码添加客服微信,咨询产品报价