Human C1qTNF1 ELISA Kit ELISA试剂盒,Human C1qTNF1 ELISA Kit/人C1qTNF1 ELISA试剂盒

2024-10-24

Human C1qTNF1 ELISA Kit/人C1qTNF1 ELISA试剂盒

货号:EH53RB,EH53RBX5,EH53RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.61 ng/mL

检测范围0.61-150 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameCTRP1
Protein aliasesComplement C1q tumor necrosis factor-related protein 1, G protein coupled receptor interacting protein, G protein-coupled receptor-interacting protein, GIP

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesC1QTNF1, CTRP1, GIP, UNQ310/PRO353, ZSIG37
Gene ID(Human) 114897
Gene symbolC1QTNF1
UniProt ID(Human) Q9BXJ1
Human C1qTNF1 quantitates human C1qTNF1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human C1qTNF1.人C1qTNF1定量检测血清,血浆,上清液中的人C1qTNF1。 该检测试剂盒将专门识别天然和重组人C1qTNF1。Target information 靶标信息Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. In obese (ob/ob) mice, RT-PCR analysis showed that mCTRP1 transcripts are seen at substantially higher levels in adipose tissues compared to those of normal mice.生物体的脂肪组织通过产生和分泌多种被称为脂肪因子的生物活性分子,在调节生理和病理过程(例如新陈代谢和免疫)中起主要作用。一个高度保守的脂肪因子家族是脂联素/ ACRP30及其结构和功能旁系同源物C1q /肿瘤坏死因子-α相关蛋白(CTRP)1-7。与仅由分化的脂肪细胞表达的脂连蛋白不同,CTRP在各种各样的组织中表达。这些蛋白质被认为主要作用于肝脏和肌肉组织,以控制葡萄糖和脂质的代谢。脂联素的晶体结构分析揭示了TNF和含C1q的蛋白之间的结构和进化联系,表明这些蛋白源自共同的祖先先天免疫基因。在肥胖(ob / ob)小鼠中,RT-PCR分析显示,与正常小鼠相比,在脂肪组织中看到的mCTRP1转录本水平高得多。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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