Human CD34 ELISA Kit ELISA试剂盒,Human CD34 ELISA Kit/人CD34 ELISA试剂盒

2024-10-24

Human CD34 ELISA Kit/人CD34 ELISA试剂盒

货号:EH86RB,EH86RBX5,EH86RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.05 ng/mL

检测范围0.05-10 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameCD34
Protein aliasesCD34, CD34 antigen, Hematopoietic progenitor cell antigen CD34

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesCD34
Gene ID(Human) 947
Gene symbolCD34
UniProt ID(Human) P28906
Human CD34 quantitates human CD34 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CD34.人CD34定量测定血清,血浆,上清液中的人CD34。 该检测试剂盒将专门识别天然和重组人CD34。Target information 靶标信息CD34 is a highly glycosylated monomeric with a molecular weight range of 111-115 kDa surface protein that is present on many stem cell populations. CD34 is a stem cell marker although its expression on human hematopoietic stem cells is reversible. CD34 may serve as a surface receptor that undergoes receptor-mediated endocytosis and regulates adhesion, differentiation and proliferation of hematopoietic stem cells and other progenitors. CD34 expression is likely to represent a specific state of hematopoietic development that may have altered adhering properties with expanding and differentiating capabilities in both in vitro and in vivo conditions. CD34 is possibly an adhesion molecule with a putative role for mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Further, CD34 could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is thought to have a role in presenting carbohydrate ligands to selectins. The intracellular chain of the CD34 antigen is a site of phosphorylation by activated protein kinase C suggesting a putative role in signal transduction. Diseases associated with CD34 dysfunction include dermatofibrosarcoma and neurofibroma.CD34是高度糖基化的单体,分子量范围为111-115 kDa,存在于许多干细胞群体中。 CD34是干细胞标记,尽管其在人造血干细胞上的表达是可逆的。 CD34可以用作表面受体,该表面受体经历受体介导的内吞作用并调节造血干细胞和其他祖细胞的粘附,分化和增殖。 CD34表达可能代表造血细胞发育的特定状态,在体外和体内条件下,其粘附特性都会发生改变,并具有扩展和分化的能力。 CD34可能是一种粘附分子,可能具有介导干细胞附着于骨髓细胞外基质或直接附着于基质细胞的作用。此外,CD34可以作为支架用于谱系特异性聚糖的附着,从而使干细胞与基质细胞或其他骨髓成分表达的凝集素结合。 CD34被认为在向选择素呈递碳水化合物配体中起作用。 CD34抗原的细胞内链是被激活的蛋白激酶C磷酸化的位点,提示在信号转导中可能发挥了作用。与CD34功能障碍相关的疾病包括皮肤纤维肉瘤和神经纤维瘤。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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