Human CD63 ELISA Kit ELISA试剂盒,Human CD63 ELISA Kit/人CD63 ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Human CD63 ELISA Kit ELISA试剂盒,Human CD63 ELISA Kit/人CD63 ELISA试剂盒

2024-10-24

Human CD63 ELISA Kit/人CD63 ELISA试剂盒

货号：EH95RB,EH95RBX5,EH95RBX10

规格：96 tests,5X96 tests,10X96 tests

价格：6641,29884,57271

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：人

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	14 pg/mL
检测范围	14-3,000 pg/mL
样本类型/体积	血清 50 μL 血浆 50 μL 上清液 50 μL
操作时间	1 hr 20 min
测试时间	4 hr 45 min
Homogenous (no wash)	No
批间变异系数（CV）	<12%
批内变异系数（CV）	<10%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	5 x 96 Tests
组份	- 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	CD63
Protein aliases	CD63, CD63 antigen, CD63 antigen (melanoma 1 antigen), Granulophysin, LAMP-3, Lysosomal-associated membrane protein 3, lysosome-associated membrane glycoprotein 3, Melanoma-associated antigen ME491, melanoma-associated antigen MLA1, Ocular melanoma-associated antigen, OMA81H, Tetraspanin-30, Tspan-30
物种（Tested）	人
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	CD63, LAMP-3, ME491, MLA1, OMA81H, TSPAN30
Gene ID	(Human) 967
Gene symbol	CD63
UniProt ID	(Human) P08962

Human CD63 quantitates human CD63 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CD63.人CD63定量检测血清，血浆，上清液中的人CD63。该检测试剂盒将专门识别天然和重组人CD63。Target information 靶标信息CD63 (LAMP-3, lysosome-associated membrane protein-3), a glycoprotein of tetraspanin family, is present in late endosomes, lysosomes and secretory vesicles of various cell types. CD63 is also present in the plasma membrane, usually following cell activation. Hence, CD63 has become a widely used basophil activation marker. In mast cells, however, CD63 exposition does not need their activation. CD63 interacts with integrins and affects phagocytosis and cell migration, it is also involved in H/K-ATPase trafficking regulation of ROMK1 channels. CD63 also serves as a T-cell costimulation molecule. Expression of CD63 can be used for predicting the prognosis in earlier stages of carcinomas. CD63 is expressed on activated platelets, and is a lysosomal membrane glycoprotein that is translocated to plasma membrane after platelet activation. CD63 is also present in monocytes and macrophages and is weakly expressed on granulocytes, B, and T cells. CD63 is identical to the melanoma-associated antigen which is ME491 and to the platelet antigen PTLGP40. Diseases associated with CD63 dysfunction include melanoma and Hermansky-Pudlak Syndrome.CD63（LAMP-3，与溶酶体相关的膜蛋白3），一种四跨膜蛋白家族的糖蛋白，存在于各种细胞类型的晚期内体，溶酶体和分泌小泡中。通常在细胞活化后，CD63也存在于质膜中。因此，CD63已经成为广泛使用的嗜碱性粒细胞活化标记。然而，在肥大细胞中，CD63暴露不需要激活。 CD63与整联蛋白相互作用并影响吞噬作用和细胞迁移，它还参与ROMK1通道的H / K-ATPase转运调节。 CD63还用作T细胞共刺激分子。 CD63的表达可用于预测癌症早期阶段的预后。 CD63在活化的血小板上表达，是一种溶酶体膜糖蛋白，在血小板活化后易位至质膜。 CD63也存在于单核细胞和巨噬细胞中，并在粒细胞，B和T细胞中弱表达。 CD63与黑色素瘤相关抗原ME491和血小板抗原PTLGP40相同。与CD63功能障碍有关的疾病包括黑色素瘤和赫曼斯基-普德勒克综合症。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

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Human CD63 ELISA Kit ELISA试剂盒,Human CD63 ELISA Kit/人CD63 ELISA试剂盒

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