Human AMICA ELISA Kit ELISA试剂盒,Human AMICA ELISA Kit/人AMICA ELISA试剂盒

2024-10-24

Human AMICA ELISA Kit/人AMICA ELISA试剂盒

货号:EH22RB,EH22RBX5,EH22RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.41 ng/mL

检测范围0.41-100 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameAMICA
Protein aliasesadhesion molecule AMICA, Adhesion molecule interacting with CXADR antigen 1, adhesion molecule, interacts with CXADR antigen 1, Dendritic cell-specific protein CREA7-1, dendritic-cell specific protein CREA7-1, dendritic-cell specific protein CREA7-4, Junctional adhesion molecule-like

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesAMICA, AMICA1, CREA7-1, CREA7-4, Gm638, JAML, UNQ722/PRO1387
Gene ID(Human) 120425
Gene symbolJAML
UniProt ID(Human) Q86YT9
Human AMICA quantitates human AMICA in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human AMICA.人AMICA定量测定血清,血浆,上清液中的人AMICA。该检测试剂盒将专门识别天然和重组人AMICA。Target information 靶标信息AMICA transmembrane protein of the plasma membrane of leukocytes that control their migration and activation through interaction with CXADR, a plasma membrane receptor found on adjacent epithelial and endothelial cells. The interaction between both receptors mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair. It also controls the transmigration of leukocytes within epithelial and endothelial tissues through adhesive interactions with epithelial and endothelial CXADR.白细胞质膜的AMICA跨膜蛋白,可通过与CXADR相互作用来控制其迁移和激活,CXADR是在邻近的上皮和内皮细胞上发现的质膜受体。两种受体之间的相互作用介导了γ-δT细胞的活化,γ-T细胞是驻留在上皮细胞中并参与组织稳态和修复的T细胞亚群。在上皮CXADR结合后,JAML通过PI3激酶和MAP激酶在γ-δT细胞中诱导下游细胞信号转导事件。它导致T细胞增殖,产生细胞因子和生长因子,进而刺激上皮组织修复。它还通过与上皮和内皮CXADR的粘着相互作用来控制白细胞在上皮和内皮组织内的迁移。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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