Human GPVI ELISA Kit ELISA试剂盒,Human GPVI ELISA Kit/人GPVI ELISA试剂盒

2024-10-24

Human GPVI ELISA Kit/人GPVI ELISA试剂盒

货号:EH230RB,EH230RBX5,EH230RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

26 pg/mL

检测范围26-6,000 pg/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameGP6
Protein aliasesGlycoprotein 6, glycoprotein VI (platelet), GPVI, platelet collagen receptor, Platelet glycoprotein VI

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesBDPLT11, GP6, GPIV, GPVI
Gene ID(Human) 51206
Gene symbolGP6
UniProt ID(Human) Q9HCN6
Human GPVI quantitates human GPVI in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human GPVI.人GPVI定量测定血清,血浆,上清液中的人GPVI。该检测试剂盒将专门识别天然和重组人GPVI。Target information 靶标信息Glycoprotein VI (GP6) is a 58-kD platelet membrane glycoprotein that plays a crucial role in the collagen-induced activation and aggregation of platelets. Upon injury to the vessel wall and subsequent damage to the endothelial lining, exposure of the subendothelial matrix to blood flow results in deposition of platelets. Collagen fibers are the most thrombogenic macromolecular components of the extracellular matrix, with collagen types I, III, and VI being the major forms found in blood vessels. Platelet interaction with collagen occurs as a 2-step procedure: (1) the initial adhesion to collagen is followed by (2) an activation step leading to platelet secretion, recruitment of additional platelets, and aggregation. In physiologic conditions, the resulting platelet plug is the initial hemostatic event limiting blood loss. However, exposure of collagen after rupture of atherosclerotic plaques is a major stimulus of thrombus formation associated with myocardial infarction or stroke.糖蛋白VI(GP6)是58 kD的血小板膜糖蛋白,在胶原蛋白诱导的血小板活化和聚集中起关键作用。在损伤血管壁并随后损坏内皮内膜时,内皮下基质暴露于血流导致血小板沉积。胶原蛋白纤维是细胞外基质中最具血栓形成性的大分子成分,其中I,III和VI型胶原蛋白是血管中发现的主要形式。血小板与胶原蛋白的相互作用分两步进行:(1)最初与胶原蛋白的粘附,然后是(2)激活步骤,导致血小板分泌,募集更多的血小板和聚集。在生理条件下,产生的血小板堵塞是限制血液流失的最初止血事件。然而,动脉粥样硬化斑块破裂后胶原蛋白的暴露是与心肌梗塞或中风相关的血栓形成的主要刺激。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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