Human IL-17 RB ELISA Kit ELISA试剂盒,Human IL-17 RB ELISA Kit/人IL-17 RB ELISA试剂盒

2024-10-24

Human IL-17 RB ELISA Kit/人IL-17 RB ELISA试剂盒

货号:EH261RB,EH261RBX5,EH261RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6327,28472,54564

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.85 ng/mL

检测范围0.85-200 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameIL17RB
Protein aliasescytokine receptor CRL4, Cytokine receptor-like 4, IL-17 receptor B, IL-17 receptor homolog 1, IL-17B receptor, IL-17RB, IL-17Rh1, interleukin 17 receptor homolog 1, interleukin 17B receptor, Interleukin-17 receptor B, Interleukin-17B receptor

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesCRL4, EVI27, IL17BR, IL17RB, IL17RH1, UNQ2501/PRO19612
Gene ID(Human) 55540
Gene symbolIL17RB
UniProt ID(Human) Q9NRM6
Human IL-17 RB quantitates human IL-17 RB in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human IL-17 RB.人IL-17 RB定量测定血清,血浆,上清液中的人IL-17 RB。该检测试剂盒将只识别天然和重组人IL-17 RB。Target information 靶标信息Recently, a number of cytokines belonging to the interleukin (IL)-17 family have been identified. These are termed as IL-17B, IL-17C (1) and IL-17E. IL-17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis, multiple sclerosis, and promotion of tumor growth. IL-17B, C, and E like IL-17 are able to induce proinflammatory responses. However, they do not bind to the IL-17 receptor suggesting that additional IL-17R related receptor might exist. Receptor for IL-17B and IL-17E has been independently isolated and has been designated as EV127 (in mouse) and IL-17Rh1 (in human), respectively. IL-17E induces activation of NF-kB pathway and like IL-17 also induces production of IL-8. IL-17Rh1 mRNA is highly expressed in Kidney and liver and at moderate level in small intestine, colon, and brain.最近,已经鉴定出许多属于白介素(IL)-17家族的细胞因子。这些被称为IL-17B,IL-17C(1)和IL-17E。 IL-17是一种有效的促炎细胞因子,可在多种疾病中发挥作用,包括类风湿性关节炎,多发性硬化和促进肿瘤生长。 IL-17B,C和E像IL-17一样能够诱导促炎反应。但是,它们不与IL-17受体结合,表明可能存在其他与IL-17R相关的受体。 IL-17B和IL-17E的受体已独立分离,分别命名为EV127(小鼠)和IL-17Rh1(人类)。 IL-17E诱导NF-kB途径的激活,并且像IL-17一样也诱导IL-8的产生。 IL-17Rh1 mRNA在肾脏和肝脏中高表达,在小肠,结肠和脑中呈中等水平。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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