Human Semaphorin 4D ELISA Kit ELISA试剂盒,Human Semaphorin 4D ELISA Kit/人Semaphorin 4D ELISA试剂盒

2024-10-24

Human Semaphorin 4D ELISA Kit/人Semaphorin 4D ELISA试剂盒

货号:EH405RB,EH405RBX5,EH405RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6327,28472,54564

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.62 ng/mL

检测范围0.62-150 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameCD100 (SEMA4D)
Protein aliasesA8, BB18, CD100, GR3, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D, 4D, Semaphorin-4D

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesC9orf164, CD100, coll-4, M-sema-G, SEMA4D, SEMAJ
Gene ID(Human) 10507
Gene symbolSEMA4D
UniProt ID(Human) Q92854
Human Semaphorin 4D quantitates human Semaphorin 4D in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Semaphorin 4D.人Semaphorin 4D定量分析血清,血浆,上清液中的人Semaphorin 4D。 该检测试剂盒将专门识别天然和重组人Semaphorin 4D。Target information 靶标信息Semaphorins are neuronal chemorepellants that direct pioneering neurons during nervous system development. CD100 (also known as semaphorin 4d), a 150 kDa homodimer, is a novel semaphorin that induces B cells to aggregate and improves their viability in vitro. CD100 modifies CD40-CD40L B cell signaling by augmenting B cell aggregation and survival and down regulating CD23 expression. CD72 is a lymphocyte receptor for the class IV semaphorin CD100, which is involved in regulating B cell signaling. CD100 is expressed on resting and PHA stimulated T cells. The protein is weakly expressed on NK cells, EBV transformed B cells, monocytes and tumor/peripheral blood T cell lines, and at higher density on activated T cells and B cells.信号量是神经元化学趋化剂,可在神经系统发育过程中引导先驱神经元。 150 kDa的同型二聚体CD100(也称为信号量4d)是一种新型的信号量,可以诱导B细胞聚集并提高其在体外的生存能力。 CD100通过增加B细胞聚集和存活以及下调CD23表达来修饰CD40-CD40L B细胞信号传导。 CD72是IV类信号量CD100的淋巴细胞受体,参与调节B细胞信号传导。 CD100在静止和PHA刺激的T细胞上表达。 该蛋白在NK细胞,EBV转化的B细胞,单核细胞和肿瘤/外周血T细胞系上表达较弱,而在活化T细胞和B细胞上则以较高的密度表达。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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