Human Transglutaminase 2/TGM2 ELISA Kit ELISA试剂盒,Human Transglutaminase 2/TGM2 ELISA Kit/人转谷氨酰胺酶2 / TGM2 ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Human Transglutaminase 2/TGM2 ELISA Kit ELISA试剂盒,Human Transglutaminase 2/TGM2 ELISA Kit/人转谷氨酰胺酶2 / TGM2 ELISA试剂盒

2024-10-24

Human Transglutaminase 2/TGM2 ELISA Kit/人转谷氨酰胺酶2 / TGM2 ELISA试剂盒

货号：EH462RB,EH462RBX5,EH462RBX10

规格：96 tests,5X96 tests,10X96 tests

价格：6641,29884,57271

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：人

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	0.82 ng/mL
检测范围	0.82-200 ng/mL
样本类型/体积	血清 50 μL 血浆 50 μL 上清液 50 μL
操作时间	1 hr 20 min
测试时间	4 hr 45 min
Homogenous (no wash)	No
批间变异系数（CV）	<12%
批内变异系数（CV）	<10%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	5 x 96 Tests
组份	- 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	TGM2
Protein aliases	C polypeptide, protein-glutamine-gamma-glutamyltransferase, Protein-glutamine gamma-glutamyltransferase 2, TG(C), TGase C, TGase H, TGase-2, Tissue transglutaminase, Transglutaminase C, Transglutaminase H, Transglutaminase-2
物种（Tested）	人
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	TG(C), TGC, TGM2
Gene ID	(Human) 7052
Gene symbol	TGM2
UniProt ID	(Human) P21980

Human Transglutaminase 2/TGM2 quantitates human Transglutaminase 2/TGM2 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Transglutaminase 2/TGM2.人转谷氨酰胺酶2 / TGM2定量检测血清，血浆，上清液中的人转谷氨酰胺酶2 / TGM2。该检测试剂盒将专门识别天然和重组人转谷氨酰胺酶2 / TGM2。Target information 靶标信息Transglutaminase (TGase) catalyses the crosslink of proteins by forming e-(g-glutamyl) lysine isopeptide bonds and requires the binding of Ca2+ for its activity. In mammals, eight distinct TGase isoenzymes have been identified. Tissue transglutaminase (tTGase), also known as TGase 2, has four distinct domains: N-terminal b-sandwich, catalytic core and two C-terminal b-barrel domains. tTGase may have a role in cell death, cell proliferation, cell differentiation, and receptor-mediated endocytosis. In the Alzheimer's disease brain, the elevated tTGase activity is manifested by polymerization of a number of proteins, including Ab peptide, b-amyloid precursor protein and the tau protein, with formation of neurofibrillary tangles.转谷氨酰胺酶（TGase）通过形成e-（g-谷氨酰基）赖氨酸异肽键来催化蛋白质的交联，并且需要Ca2 +的结合才能发挥其活性。在哺乳动物中，已鉴定出八种不同的TGase同工酶。组织转谷氨酰胺酶（tTGase），也称为TGase 2，具有四个不同的域：N端b三明治，催化核心和两个C端b桶结构域。 tTGase可能在细胞死亡，细胞增殖，细胞分化和受体介导的内吞作用中起作用。在阿尔茨海默氏病脑中，tTGase活性升高是由许多蛋白（包括Ab肽，b淀粉样前体蛋白和tau蛋白）聚合并形成神经原纤维缠结而表现出来的。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

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Human Transglutaminase 2/TGM2 ELISA Kit ELISA试剂盒,Human Transglutaminase 2/TGM2 ELISA Kit/人转谷氨酰胺酶2 / TGM2 ELISA试剂盒

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