Human VEGF-B ELISA Kit ELISA试剂盒,Human VEGF-B ELISA Kit/人VEGF-B ELISA试剂盒

2024-10-24

Human VEGF-B ELISA Kit/人VEGF-B ELISA试剂盒

货号:EH481RB,EH481RBX5,EH481RBX10

规格:96 tests,5X96 tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.4 ng/mL

检测范围0.4-100ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameVEGFB
Protein aliasesVascular endothelial growth factor B, VEGF-B, VEGF-related factor, VRF

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesVEGFB, VEGFL, VRF
Gene ID(Human) 7423
Gene symbolVEGFB
UniProt ID(Human) P49765
Human VEGF-B quantitates human VEGF-B in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human VEGF-B.人VEGF-B定量测定血清,血浆,上清液中的人VEGF-B。该检测试剂盒将只识别天然和重组人VEGF-B。Target information 靶标信息Vascular endothelial growth factors (VEGFs) are a family of closely related growth factors having a conserved pattern of eight cysteine residues and sharing common VEGF receptors. VEGFs stimulate endothelial cells, induce angiogenesis, promote cell migration, increase vascular permeability, and inhibit apoptosis. VEGFB has structural similarities to VEGF and PIGF and is frequently co-expressed with VEGF. There are two alternatively spliced isoforms of VEGFB: VEGFB 167 and VEGFB 186. VEGFB 167, a highly basic heparin-binding protein, remains with the cell or extracellular matrix whereas, VEGFB 186 is readily secreted. VEGFB stimulates endothelial cell proliferation. VEGFB binds to the tyrosine kinase receptor VEGFR1 (flt1) and does not bind to VEGFR2. Vascular Endothelial Growth Factor B is widely expressed but is most abundant in heart, skeletal muscle, and pancreas. It has been suggested that VEGFB expression in human primary breast cancers is associated with lymph node metastasis. The genes that encode VEGFB have been mapped to chromosome 11q13.血管内皮生长因子(VEGF)是一类密切相关的生长因子,具有八个半胱氨酸残基的保守模式,并具有共同的VEGF受体。 VEGF刺激内皮细胞,诱导血管生成,促进细胞迁移,增加血管通透性并抑制细胞凋亡。 VEGFB与VEGF和PIGF具有结构相似性,并经常与VEGF共表达。 VEGFB有两种剪接的同工型:VEGFB 167和VEGFB186。VEGFB 167是一种高度碱性的肝素结合蛋白,保留在细胞或细胞外基质中,而VEGFB 186则很容易分泌。 VEGFB刺激内皮细胞增殖。 VEGFB与酪氨酸激酶受体VEGFR1(flt1)结合,而不与VEGFR2结合。血管内皮生长因子B广泛表达,但在心脏,骨骼肌和胰腺中含量最高。已经提出,人原发性乳腺癌中的VEGFB表达与淋巴结转移有关。编码VEGFB的基因已定位到11q13号染色体。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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