Human TfR/Transferrin R/CD71 ELISA Kit ELISA试剂盒,Human TfR/Transferrin R/CD71 ELISA Kit/人TfR /转铁蛋白R / CD71 ELISA试剂盒

2024-10-24

Human TfR/Transferrin R/CD71 ELISA Kit/人TfR /转铁蛋白R / CD71 ELISA试剂盒

货号:EH448RB,EH448RBX5,EH448RBX10

规格:96 Tests,5X96 Tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.81 ng/mL

检测范围0.819-200 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameTransferrin Receptor (CD71)
Protein aliasesCD71, p90, sTfR, T9, TR, Transferrin receptor protein 1, serum form

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesCD71, IMD46, p90, T9, TFR, TFR1, TFRC, TR, TRFR
Gene ID(Human) 7037
Gene symbolTFRC
UniProt ID(Human) P02786
Human TfR/Transferrin R/CD71 quantitates human TfR/Transferrin R/CD71 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human TfR/Transferrin R/CD71.人TfR /转铁蛋白R / CD71定量测定血清,血浆,上清液中的人TfR /转铁蛋白R / CD71。 该检测试剂盒将专门识别天然和重组人TfR /转铁蛋白R / CD71。Target information 靶标信息Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.细胞对铁的摄取是通过配体占据的转铁蛋白受体经受体介导的内吞作用进入专门的内体。 内体酸化导致铁释放。 然后将载铁蛋白-受体复合物再循环到细胞表面,恢复到中性pH,并随之丧失载铁蛋白对其受体的亲和力。 转铁蛋白受体对于红细胞和神经系统的发育是必需的。 血清转铁蛋白受体(sTfR)用作检测运动员滥用促红细胞生成素(EPO)的手段,以及对多种疾病引起的贫血的诊断测试,包括风湿性关节炎,妊娠,肠易激综合征和HIV患者。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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