组蛋白甲基化修饰,H4K36,单克隆抗体,NSD2 Monoclonal Antibody (CL1057)

2024-10-24

NSD2 Monoclonal Antibody (CL1057)

货号:MA5-24620

规格:100 µL

价格:5548

产品类型:标签抗体

品牌:Thermo Fisher

抗原:Recombinant protein corresponding to Human NSD2

物种:人

宿主:小鼠

抗体亚型:IgG1, kappa

克隆号:CL1057

荧光染料:其它

类型:一抗同型对照:
浓度: 1 mg/mL用法: 2-10 µg/mL(ICC) ;2-10 µg/mL(IF);1:200-1:500(IHC)
产品详细信息Immunogen sequence: SANGKTPSCE VNRECSVFLS KAQLSSSLQE GVMQKFNGHD ALPFIPADKL KDLTSRVFNG EPGAHDAKLR FESQEMKGIG TPPNTTPIKN GSPEIKLKIT KTYMNGKPLF ESSICGDHighest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 91%.Binds to an epitope located within the peptide sequence RVFNGEPGAHDAKLR as determined by overlapping synthetic peptides. 靶标信息This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.
数据:

NSD2 Antibody (MA5-24620) in ICC Immunocytochemistry-Immunofluorescence analysis of NSD2 in U-251 cells using NSD2 Monoclonal Antibody (CL1057) (Product # MA5-24620), showing specific staining in the nucleoplasm in green. Microtubule- and nuclear probes are visualized in red and blue, respectively (where available).

NSD2 Antibody (MA5-24620) in IHC Immunohistochemical staining of NSD2 in human colorectal cancer shows strong nuclear immunoreactivity in tumor cells. Samples were probed using a NSD2 Monoclonal Antibody (Product # MA5-24620).
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