Human Coagulation Factor XIV/Protein C ELISA Kit ELISA试剂盒,Human Coagulation Factor XIV/Protein C ELISA Kit/人凝血因子XIV /蛋白C ELISA

2024-10-24

Human Coagulation Factor XIV/Protein C ELISA Kit/人凝血因子XIV /蛋白C ELISA试剂盒

货号:EH119RB,EH119RBX5,EH119RBX10

规格:96 Tests,5X96 Tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.82 ng/mL

检测范围0.82-20 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameProtein C
Protein aliasesActivation peptide, Anticoagulant protein C, Autoprothrombin IIA, Blood coagulation factor XIV, prepro-protein C, protein C (inactivator of coagulation factors Va and VIIIa), type I protein C, Vitamin K-dependent protein C, Vitamin K-dependent protein C heavy chain, Vitamin K-dependent protein C light chain

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesAPC, PC, PROC, PROC1, THPH3, THPH4
Gene ID(Human) 5624
Gene symbolPROC
UniProt ID(Human) P04070
Human Coagulation Factor XIV/Protein C quantitates human Coagulation Factor XIV/Protein C in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Coagulation Factor XIV/Protein C.人凝血因子XIV /蛋白C定量测定血清,血浆,上清液中的人凝血因子XIV /蛋白C。该检测试剂盒将专门识别天然和重组人凝血因子XIV /蛋白C。Target information 靶标信息Protein C is a vitamin K-dependent plasma glycoprotein that is cleaved to its activated form by the thrombin-thrombomodulin complex. Protein C in its activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Protein C is a vitamin K-dependent serine protease produced in the liver and made up of 2 polypeptide chains. The 62 kDa proenzyme is activated by thrombin bound to an endothelial surface receptor and the active enzyme cleaves factor Va and VIIIa and thus inhibits blood coagulation. The molecular weight of the active enzyme is 55kDa and the normal concentrations in human plasma is approximately 1-3 ng/ml because of the very fast turnover, the proenzyme concentration is approximately 3 µg/ml. Mutations in the Protein C gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.蛋白C是依赖维生素K的血浆糖蛋白,可被凝血酶-血栓调节蛋白复合物切割成其活化形式。活化形式的蛋白C包含一个丝氨酸蛋白酶结构域,并在凝血因子V和VIII活化形式的降解中起作用。蛋白C是在肝脏中产生的维生素K依赖性丝氨酸蛋白酶,由2条多肽链组成。 62 kDa的原酶被结合到内皮表面受体的凝血酶激活,而活性酶裂解因子Va和VIIIa,从而抑制血液凝结。活性酶的分子量为55kDa,由于周转速度非常快,人血浆中的正常浓度约为1-3 ng / ml,原酶的浓度约为3 µg / ml。蛋白C基因的突变与蛋白C缺乏症,新生儿紫癜性暴发和复发性静脉血栓形成有关,与血栓形成有关。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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