Human IFN alpha/beta R2 ELISA Kit ELISA试剂盒,Human IFN alpha/beta R2 ELISA Kit/人IFN alpha / beta R2 ELISA试剂盒

2024-10-24

Human IFN alpha/beta R2 ELISA Kit/人IFN alpha / beta R2 ELISA试剂盒

货号:EH248RB,EH248RBX5,EH248RBX10

规格:96 Tests,5X96 Tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.16 ng/mL

检测范围0.16-40 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameIFNAR2
Protein aliaseshuman interferon alpha/beta receptor, IFN-alpha/beta receptor 2, IFN-R-2, interferon (alpha, beta and omega) receptor 2, Interferon alpha binding protein, Interferon alpha/beta receptor 2, interferon-alpha/beta receptor beta chain, Type I interferon receptor 2

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesIFN-alpha-REC, IFN-R, IFNABR, IFNAR2, IFNARB, IMD45
Gene ID(Human) 3455
Gene symbolIFNAR2
UniProt ID(Human) P48551
Human IFN alpha/beta R2 quantitates human IFN alpha/beta R2 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human IFN alpha/beta R2.人IFNα/ beta R2定量检测血清,血浆,上清液中的人IFN alpha / beta R2。该检测试剂盒将专门识别天然和重组人IFNα/βR2。Target information 靶标信息The type I interferons, IFN-alpha and IFN-beta, are a group of structurally and functionally related proteins that are induced by either viruses or double-stranded RNA and are defined by their ability to confer an antiviral state in cells. IFN-alpha and IFN-beta appear to compete with one another for binding to a common cell surface receptor, while immune IFN (IFN-gamma) binds to a distinct receptor. This distinct receptor, IFN-alphaR, is only weakly responsive to type I interferons, in contrast to IFN-alpha/betaR, which binds to and responds effectively to IFN-beta and to several of the IFN-alpha subtypes. IFN-alpha/betaR is expressed as two alternatively spliced transcripts, designated IFN-alpha/betaRalpha (IFN-alpha/betaR1) and IFN-alpha/betaRbeta (IFN-alpha/betaR2), both of which are involved in signal transduction and ligand binding.I型干扰素IFN-α和IFN-β是一组在结构和功能上相关的蛋白质,它们被病毒或双链RNA诱导,并通过它们在细胞中赋予抗病毒状态的能力来定义。 IFN-α和IFN-β似乎彼此竞争结合一种共同的细胞表面受体,而免疫IFN(IFN-γ)则结合一种独特的受体。与IFN-alpha / betaR相比,该独特的受体IFN-alphaR对I型干扰素的反应较弱,后者与IFN-beta和几种IFN-alpha亚型结合并对其产生有效反应。 IFN-alpha / betaR表达为两个选择性剪接的转录本,分别称为IFN-alpha / betaRalpha(IFN-alpha / betaR1)和IFN-alpha / betaRbeta(IFN-alpha / betaR2),两者均参与信号转导和配体捆绑。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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