Human Nogo-A/Reticulon 4A ELISA Kit ELISA试剂盒,Human Nogo-A/Reticulon 4A ELISA Kit/人Nogo-A / Reticulon 4A ELISA试剂盒

2024-10-24

Human Nogo-A/Reticulon 4A ELISA Kit/人Nogo-A / Reticulon 4A ELISA试剂盒

货号:EH343RB,EH343RBX5,EH343RBX10

规格:96 Tests,5X96 Tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:人

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.42 ng/mL

检测范围0.42-100 ng/mL

样本类型/体积

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameNogo-A
Protein aliasesFoocen, Human NogoA, My043 protein, neurite growth inhibitor 220, Neurite outgrowth inhibitor, Neuroendocrine-specific protein, Neuroendocrine-specific protein C homolog, Nogo protein, NSP, reticulon 5, Reticulon-4, Reticulon-5, RTN-x

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesASY, KIAA0886, My043, Nbla00271, Nbla10545, NI220/250, NOGO, NOGO-A, Nogo-B, Nogo-C, NOGOC, NSP, NSP-CL, RTN-X, RTN4, RTN4-A, RTN4-B1, RTN4-B2, RTN4-C, SP1507
Gene ID(Human) 57142
Gene symbolRTN4
UniProt ID(Human) Q9NQC3
Human Nogo-A/Reticulon 4A quantitates human Nogo-A/Reticulon 4A in supernatant. The assay will exclusively recognize both natural and recombinant human Nogo-A/Reticulon 4A.人Nogo-A /网状蛋白4A定量测定上清液中的人Nogo-A /网状蛋白4A。该检测试剂盒将专门识别天然和重组人Nogo-A /网状蛋白4A。Target information 靶标信息NogoA is a member of a family of integral membrane proteins termed reticulons that are thought to be involved in numerous disorders including neurodegenerative diseases. Reticulon proteins are known to regulate many cellular processes and interact with multiple proteins and receptors such as BACE. NogoA was initially identified as a myelin-associated neurite outgrowth inhibitor. It is highly expressed in oligodendrocytes in the white matter of the CNS, blocking its activity with antibodies or other factors results in improved axon regrowth and functional recovery in experimental CNS lesion models. NogoA has also been suggested to play a role in neurodegenerative diseases such as Amyotrophic lateral sclerosis, in which case NogoA is found at elevated levels in postmortem muscular samples, and multiple sclerosis (MS), in which case autoantibodies to NogoA have been found in serum and cerebrospinal fluid in MS patients.NogoA是被称为网状蛋白的整合膜蛋白家族的成员,被认为与包括神经退行性疾病在内的多种疾病有关。已知网织蛋白调节许多细胞过程并与多种蛋白和受体如BACE相互作用。最初,NogoA被确定为髓鞘相关的神经突增生抑制剂。它在中枢神经系统白质中的少突胶质细胞中高度表达,在抗体中或其他因素的作用下阻断其活性,从而改善了实验中枢神经系统病变模型中的轴突再生和功能恢复。还提示NogoA在神经退行性疾病如肌萎缩性侧索硬化中起作用,在这种情况下,在尸检肌肉样品中发现NogoA的水平升高,而在多发性硬化症(MS)中,在血清中发现了对NogoA的自身抗体。和MS患者的脑脊液。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

技术参数
© bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪是专业的授权总代理区域代理经销平台。
© 如需询价,请加客服QQ:1749072012 、客服微信:jinshanbio,或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务,数据资源基于CC协议。
© 本文地址:https://gibcohyclone.cn/thread-47242.htm
产品询价需求提交
返回
扫码添加客服微信,咨询产品报价