PKC delta Recombinant Rabbit Monoclonal Antibody (JJ093-02)

货号：MA5-32482

规格：100 µL

价格：4732

产品类型：标签抗体

品牌：Thermo Fisher

抗原：Mouse PKC delta aa 500 to the C-terminus

物种：人/小鼠/大鼠

宿主：兔

抗体亚型：IgG

克隆号：JJ093-02

荧光染料：其它

类型:	一抗	同型对照：
浓度：	1 mg/mL	用法：	1:50-1:200(ICC);1:50-1:200(IF);1:50-1:200(IHC);1:1,000-1:2,000(WB)

产品详细信息Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. 靶标信息Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed.

数据：

PKC delta Antibody (MA5-32482) in ICC Immunocytochemical analysis of PKC delta in MCF-7 cells using a PKC delta Monoclonal antibody (Product # MA5-32482) as seen in green. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. PKC delta Antibody (MA5-32482) in IHC (P) Immunohistochemical analysis of PKC delta of paraffin-embedded Human breast carcinoma tissue using a PKC-delta Monoclonal antibody (Product #MA5-32482). Counter stained with hematoxylin.

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