Monkey uPAR ELISA Kit ELISA试剂盒,Monkey uPAR ELISA Kit/猴uPAR ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Monkey uPAR ELISA Kit ELISA试剂盒,Monkey uPAR ELISA Kit/猴uPAR ELISA试剂盒

2024-10-24

Monkey uPAR ELISA Kit/猴uPAR ELISA试剂盒

货号：EP19RB,EP19RBX5,EP19RBX10

规格：96 Tests,5X96 Tests,10X96 tests

价格：6641,29884,57271

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：非人灵长类动物

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	0.12 ng/mL
检测范围	0.12-25 ng/mL
样本类型/体积	血清 50 μL 血浆 50 μL 上清液 50 μL
操作时间	1 hr 20 min
测试时间	4 hr 45 min
Homogenous (no wash)	No
批间变异系数（CV）	<12%
批内变异系数（CV）	<10%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	5 x 96 Tests
组份	- 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	uPAR (CD87)
物种（Tested）	非人类灵长类动物
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin

Monkey uPAR quantitates monkey uPAR in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant monkey uPAR.猴uPAR定量分析血清，血浆，上清液中的猴uPAR。该检测试剂盒将专门识别天然和重组猴uPAR。Target information 靶标信息The urokinase-type plasminogen activator receptor is a key molecule in the regulation of cell-surface plasminogen activation and plays an important role in many normal as well as pathologic processes. The human PLAUR cDNA encodes 335 amino acids including a predicted signal peptide of 22 residues and a hydrophobic C-terminal portion. It produces a highly glycosylated protein of about 50 kD in monocytes where it is anchored to the plasma membrane by glycosyl-phosphatidylinositol linkage. PLAUR, also known as UPAR, is directly associated with the carbohydrate-binding domain of SELL in the membrane of neutrophils, an association analogous to that between PLAUR and beta-2 integrins. PLAUR-mediated calcium mobilization is SELL dependent. UPAR mRNA levels correlate with the invasive potential of endometrial carcinomas and show a 33-fold increase in UPAR mRNA levels in advanced clinical stage endometrial tumors compared with normal endometrial tissue. Furthermore, the increase in UPAR mRNA levels correlated linearly with the progression of disease stage. UPAR protein expressioin correlated positively with rate of recurrence and mortality in patients with endometrial cancer. UPAR appears to be a useful prognostic marker for advanced endometrial cancer.尿激酶型纤溶酶原激活剂受体是调节细胞表面纤溶酶原激活的关键分子，并在许多正常以及病理过程中发挥重要作用。人PLAUR cDNA编码335个氨基酸，其中包括22个残基的预测信号肽和疏水性C端部分。它在单核细胞中产生约50 kD的高度糖基化蛋白，并通过糖基磷脂酰肌醇键合锚定在质膜上。 PLAUR，也称为UPAR，与嗜中性粒细胞膜中SELL的糖结合结构域直接相关，类似于PLAUR和β-2整联蛋白之间的关联。 PLAUR介导的钙动员依赖于SELL。与正常子宫内膜组织相比，UPAR mRNA水平与子宫内膜癌的浸润潜能相关，并且在晚期临床子宫内膜肿瘤中显示UPAR mRNA水平增加了33倍。此外，UPAR mRNA水平的增加与疾病阶段的进展呈线性相关。 UPAR蛋白表达与子宫内膜癌患者的复发率和死亡率呈正相关。 UPAR似乎是晚期子宫内膜癌的有用预后标志物。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

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Monkey uPAR ELISA Kit ELISA试剂盒,Monkey uPAR ELISA Kit/猴uPAR ELISA试剂盒

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