Rat CD-80 ELISA Kit ELISA试剂盒,Rat CD-80 ELISA Kit/大鼠CD-80 ELISA试剂盒

2024-10-24

Rat CD-80 ELISA Kit/大鼠CD-80 ELISA试剂盒

货号:ERA6RB,ERA6RBX5

规格:96 Tests,5X96 Tests

价格:6641,29884

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:大鼠

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

1.23 ng/mL

检测范围1.23-300 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameCD80 (B7-1)
Protein aliasesCd80 a rat homolog of the human CD28/CTLA - 4 ligand (B7-1), CD80 antigen, T-lymphocyte activation antigen CD80

物种(Tested)

大鼠

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesB7-1
Gene ID(Rat) 25408
Gene symbolCd80
Rat CD-80 quantitates rat CD-80 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat CD-80.大鼠CD-80可定量测定血清,血浆,上清液中的大鼠CD-80。 该检测试剂盒将只识别天然和重组大鼠CD-80。Target information 靶标信息CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28, and of an inhibitory receptor CTLA-4 (CD152). Both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, and both molecules can also substitute for each other in this process. CD80 is rapidly induced on the surface of in vitro activated B cells, with Epstein Barr Virus (EBV) transformed B cell lines, with Burkitts lymphoma cell lines, with freshly isolated follicular B lymphoma cells, T cells, and monocytes. The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 and CTLA4 ligands of T cells. Diseases associated with CD80 dysfunction include gallbladder squamous cell carcinoma and myocarditis.CD80(B7-1)和CD86(B7-2)是T细胞关键共刺激分子CD28和抑制受体CTLA-4(CD152)的配体。 两个B7分子均在专业抗原呈递细胞上表达,并且对于T细胞活化至关重要,并且在此过程中,两个分子也可以彼此替代。 CD80可通过爱泼斯坦巴尔病毒(EBV)转化的B细胞系,伯基兹淋巴瘤细胞系,新鲜分离的滤泡性B淋巴瘤细胞,T细胞和单核细胞在体外活化的B细胞表面快速诱导。 由于与T细胞的CD28和CTLA4配体结合,B淋巴细胞活化抗原B7-1为T淋巴细胞提供了调节信号。 与CD80功能障碍有关的疾病包括胆囊鳞状细胞癌和心肌炎。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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