Rat P-Cadherin ELISA Kit ELISA试剂盒,Rat P-Cadherin ELISA Kit/大鼠P-钙黏着蛋白ELISA试剂盒

2024-10-24

Rat P-Cadherin ELISA Kit/大鼠P-钙黏着蛋白ELISA试剂盒

货号:ERA48RB,ERA48RBX5

规格:96 Tests,5X96 Tests

价格:6641,29884

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:大鼠

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.041 ng/mL

检测范围0.041-10 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameP-cadherin
Protein aliasescadherin 3, type 1, P-cadherin (placental), cadherin-3

物种(Tested)

大鼠

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene ID(Rat) 116777
Gene symbolCdh3
Rat P-Cadherin quantitates rat P-Cadherin in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat P-Cadherin.大鼠P-钙黏着蛋白定量测定血清,血浆,上清液中的大鼠P-钙黏着蛋白。该检测试剂盒将专门识别天然和重组大鼠P-钙黏着蛋白。Target information 靶标信息P-cadherin, also known as Cadherin-3, is a Type 1 cadherin protein that belongs to the cadherin superfamily. Type 1 cadherins are single-pass transmembrane proteins that have 5 extracellular cadherin repeats and an intracellular domain that binds p120-catenin and beta-catenin. Cadherins are calcium-dependent cell-cell adhesion glycoproteins responsible for a range of processes including development, wound healing, cell-cell signaling, cell growth and differentiation. P-cadherin is expressed in human fetal structures, and in adult tissues such as the basal layer of the epidermis, breast, prostate, ovary, cervix, hair follicle, and corneal endothelium. P-cadherin expression has also been reported on embryonic stem cells, and stem cells of the normal mammary gland, and hair follicle. Overexpression of P-cadherin has been associated with poor prognosis in breast, prostate, ovary, colon, and stomach carcinomas. Mutations in CDH3 are associated with congential hypotrichosis with juvenile macular dystrophy.P-钙粘着蛋白,也称为Cadherin-3,是一种1型钙粘着蛋白,属于钙粘着蛋白超家族。 1型钙粘蛋白是具有5个细胞外钙粘蛋白重复序列和结合p120-catenin和β-catenin的细胞内结构域的单程跨膜蛋白。钙黏着蛋白是钙依赖性细胞-细胞粘附糖蛋白,负责一系列过程,包括发育,伤口愈合,细胞信号传导,细胞生长和分化。 P-钙黏着蛋白在人的胎儿结构和成人组织中,例如表皮的基底层,乳房,前列腺,卵巢,子宫颈,毛囊和角膜内皮中表达。在胚胎干细胞,正常乳腺的干细胞和毛囊上也有过P-钙粘着蛋白表达的报道。 P-钙黏着蛋白的过表达与乳腺癌,前列腺癌,卵巢癌,结肠癌和胃癌的不良预后有关。 CDH3突变与少年性黄斑营养不良伴持续性睾丸下垂症有关。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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