Rabbit anti Human CAD antibody 伯乐VPA00639 人 CAD抗体 WB

2024-10-28

Rabbit anti Human CAD antibody

货号:VPA00639

规格:100 µl

市场价格:3613

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原: CAD

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti Human CAD antibodyrecognizes the DNA fragmentation factor subunit beta, also known as DNA fragmentation factor 40 kDa subunit, caspase-activated DNase, DFF40, CPAN or caspase-activated nuclease.Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been found for DFFB but the biological validity of some of these variants has not been determined (provided by RefSeq, Sep 2013).Rabbit anti Human CAD antibody detects a band of 46 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationRabbit polyclonal antibody purified by affinity chromatography.
Buffer SolutionPhosphate buffered saline.
Preservative Stabilisers0.09% Sodium Azide2% Sucrose
ImmunogenSynthetic peptide encompassing part of the middle region of human CAD
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

产品应用 WB

产品类型 多克隆抗体

推荐用于 WB

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