组蛋白乙酰化修饰,H3K4,多克隆抗体,HDAC3 Polyclonal Antibody

2024-10-24

HDAC3 Polyclonal Antibody

货号:PA5-88613

规格:100 µL

价格:4732

产品类型:标签抗体

品牌:Thermo Fisher

抗原:A synthetic peptide corresponding to a sequence wi

物种:人/小鼠/大鼠

宿主:兔

抗体亚型:IgG

荧光染料:其它

类型:一抗同型对照:
浓度: 1.16 mg/mL用法:1:50-1:200(ICC);1:50-1:200(IF);1:50-1:200(IHC(P));1:500-1:2000(WB)
产品详细信息Positive Samples: Mouse brain; Cellular Location: Cytoplasm, Nucleus, cytosol靶标信息Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
数据:

HDAC3 Antibody (PA5-88613) in ICCImmunocytochemistry-Immunofluorescence analysis of HDAC3 was performed in HeLa cells using HDAC3 Polyclonal Antibody (Product # PA5-88613) at a dilution of 1:100. Blue: DAPI for nuclear staining.

HDAC3 Antibody (PA5-88613) in IHCImmunohistochemistry analysis of HDAC3 in paraffin-embedded human colon carcinoma using HDAC3 Polyclonal Antibody (Product # PA5-88613) at a dilution of 1:200.

HDAC3 Antibody (PA5-88613) in WBWestern Blot analysis of HDAC3 in extracts of various cell lines using HDAC3 Polyclonal Antibody (Product # PA5-88613) at a dilution of 1:1000. A HRP Goat Anti-Rabbit IgG (H+L) secondary antibody was used at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
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