Porcine FGF-19 ELISA Kit ELISA试剂盒,Porcine FGF-19 ELISA Kit/猪FGF-19 ELISA试剂盒

2024-10-24

Porcine FGF-19 ELISA Kit/猪FGF-19 ELISA试剂盒

货号:ES6RB,ES6RBX5

规格:96 Tests,5X96 Tests

价格:6641,29884

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:其它

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

10 pg/mL

检测范围10-5,000 pg/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameFGF19

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene ID(Pig) 100518950
Gene symbolFGF19
Porcine FGF-19 quantitates porcine FGF-19 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant porcine FGF-19.猪FGF-19可定量测定血清,血浆,上清液中的猪FGF-19。该检测试剂盒将只识别天然和重组猪FGF-19。Target information 靶标信息FGF19, Fibroblast growth factor 19, is a protein that in humans is encoded by the FGF19 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. The FGF19 gene is mapped to 11q13.3. The deduced 216-amino acid FGF19 protein contains asignal sequence and 2 cysteine residues that are conserved in the FGF family. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development. FGF19 stimulates hepatic protein and glycogen synthesis but does not induce lipogenesis. The effects of FGF19 are independent of the activity of either insulin or the protein kinase Akt and, instead, are mediated through a mitogen-activated protein kinase signaling pathway that activates components of the protein translation machinery and stimulates glycogen synthase activity. The orthologous protein in mouse is FGF15, which shares about 50% amino acid identity and has similar functions. Together they are often referred to as FGF15/19.FGF19,成纤维细胞生长因子19,是一种在人类中由FGF19基因编码的蛋白质。该基因编码的蛋白质是成纤维细胞生长因子(FGF)家族的成员。 FGF19基因定位于11q13.3。推导的216个氨基酸的FGF19蛋白包含信号序列和2个在FGF家族中保守的半胱氨酸残基。仅在胎儿而非成人脑组织中检测到该基因的表达。已经证明雏鸡同源物和Wnt-8c的协同相互作用对于内耳发育的启动是必需的。 FGF19刺激肝蛋白和糖原合成,但不诱导脂肪生成。 FGF19的作用与胰岛素或蛋白激酶Akt的活性无关,而是通过促有丝分裂原激活的蛋白激酶信号传导途径介导的,该信号通路激活蛋白翻译机制的成分并刺激糖原合酶活性。小鼠的直系同源蛋白是FGF15,它具有大约50%的氨基酸同一性并且具有相似的功能。它们在一起通常被称为FGF15 / 19。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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