JARID1B Polyclonal Antibody

货号：IHC-00370 ,IHC-00370-T

规格：100μL,10μL

价格：6448,1886

产品类型：标签抗体

品牌：Thermo Fisher

抗原：Between 1494 and 1544

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：Alexa Fluor 488

类型:	一抗	同型对照：
浓度：	0.25 mg/mL	用法：	0.25 mg/mL(IHC)

产品详细信息The recommended shelf life for this product is 1 year from date of receipt.Based on 100% sequence identity, this antibody is predicted to react with Mouse, Dog, Panda, Orangutan, Monkey, Gorilla, Chimpanzee, Northern white-cheeked gibbon and Small-eared galago靶标信息KDM5B is a histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. It does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. KDM5B demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. It acts as a transcriptional corepressor for FOXG1B and PAX9. It favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, KDM5B may act as a tumor suppressor for melanoma.

数据：

JARID1B Antibody (IHC-00370) in IHCDetection of human JARID1B by immunohistochemistry.Sample:FFPE section of human prostate carcinoma.Antibody:Affinity purified rabbit anti-JARID1B (Cat. No. IHC-00370) used at a dilution of 1:500.Detection:DAB.

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技术参数

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