JARID1B Polyclonal Antibody
货号：IHC-00370 ,IHC-00370-T
规格：100μL,10μL
价格：6448,1886
产品类型：标签抗体
品牌：Thermo Fisher
抗原：Between 1494 and 1544
物种：人
宿主：兔
抗体亚型：IgG
荧光染料：Alexa Fluor 488
| 类型: | 一抗 | 同型对照： | |
| 浓度： | 0.25 mg/mL | 用法： | 0.25 mg/mL(IHC) |
产品详细信息The recommended shelf life for this product is 1 year from date of receipt.Based on 100% sequence identity, this antibody is predicted to react with Mouse, Dog, Panda, Orangutan, Monkey, Gorilla, Chimpanzee, Northern white-cheeked gibbon and Small-eared galago靶标信息KDM5B is a histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. It does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. KDM5B demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. It acts as a transcriptional corepressor for FOXG1B and PAX9. It favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, KDM5B may act as a tumor suppressor for melanoma.
| 数据： |
JARID1B Antibody (IHC-00370) in IHCDetection of human JARID1B by immunohistochemistry.Sample:FFPE section of human prostate carcinoma.Antibody:Affinity purified rabbit anti-JARID1B (Cat. No. IHC-00370) used at a dilution of 1:500.Detection:DAB. |
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