Bovine Fibronectin ELISA Kit ELISA试剂盒,Bovine Fibronectin ELISA Kit/牛纤连蛋白ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Bovine Fibronectin ELISA Kit ELISA试剂盒,Bovine Fibronectin ELISA Kit/牛纤连蛋白ELISA试剂盒

2024-10-24

Bovine Fibronectin ELISA Kit/牛纤连蛋白ELISA试剂盒

货号：EB4RB,EB4RBX5,EB4RBX10

规格：96 Tests,5X96 Tests,10X96 tests

价格：6327,28472,54564

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：其它

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	1.2 ng/mL
检测范围	1.2-300 ng/mL
样本类型/体积	血清 50 μL 血浆 50 μL 上清液 50 μL
操作时间	1 hr 20 min
测试时间	4 hr 45 min
Homogenous (no wash)	No
批间变异系数（CV）	<12%
批内变异系数（CV）	<10%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	5 x 96 Tests
组份	- 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	Fibronectin
Protein aliases	cumulus cell-specific fibronectin 1 transcript, embryo-specific fibronectin 1 transcript, fibronectin, fibronectin ED-A- region, fibronectin variable region
物种（Tested）	牛
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	FN
Gene ID	(Bovine) 280794
Gene symbol	FN1

Bovine Fibronectin quantitates bovine Fibronectin in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant bovine Fibronectin.牛纤连蛋白可定量测定血清，血浆，上清液中的牛纤连蛋白。该检测试剂盒将只识别天然和重组牛纤连蛋白。Target information 靶标信息Fibronectin is a disulfide-bonded dimer with a molecular weight range of 230-250 kDa. In the extracellular matrix of several connective tissues and vessels, fibronectin is present as an insoluble protein that is extensively cross-linked by interchain disulfide bonds forming high molecular mass polymers. Fibronectin is most abundant during embryonic development and tissue remodeling. Fibronectin is also present at high concentrations as a soluble plasma protein. Fibronectin is organized as a linear series of repeating modules which form domains for interaction with fibronectin itself, other matrix components (e.g. collagen and heparin) and receptors on cells (e.g. integrins). Fibronectin is present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. Fibronectin has been implicated in carcinoma development in lung cancer. Further, Fibronectin expression is increased especially in non-small cell lung carcinoma. The adhesion of lung carcinoma cells to Fibronectin enhances tumorgenecity and confers resistance to apoptosis induced by standard chemotherapeutic agents. The gene encoding Fibronectin has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some Fibronectin variants has not been determined.纤连蛋白是二硫键结合的二聚体，分子量范围为230-250 kDa。在几个结缔组织和血管的细胞外基质中，纤连蛋白作为不溶性蛋白质存在，通过链间二硫键广泛交联形成高分子聚合物。纤连蛋白在胚胎发育和组织重塑期间最丰富。纤连蛋白也作为可溶性血浆蛋白以高浓度存在。纤连蛋白被组织成一系列线性的重复模块，形成与纤连蛋白本身，其他基质组分（例如胶原蛋白和肝素）和细胞上的受体（例如整联蛋白）相互作用的结构域。纤连蛋白以可溶性二聚体形式存在于血浆中，并以二聚体或多聚体形式存在于细胞表面和细胞外基质中。纤连蛋白参与细胞粘附和迁移过程，包括胚胎发生，伤口愈合，血液凝固，宿主防御和转移。纤连蛋白与肺癌的发展有关。此外，纤连蛋白的表达增加，尤其是在非小细胞肺癌中。肺癌细胞对纤连蛋白的粘附增强了肿瘤的发生能力，并赋予了对标准化疗药物诱导的细胞凋亡的抗性。编码纤连蛋白的基因具有三个区域，这些区域需要进行可变剪接，有可能产生20种不同的转录变体。但是，尚未确定某些纤连蛋白变体的全长性质。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

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Bovine Fibronectin ELISA Kit ELISA试剂盒,Bovine Fibronectin ELISA Kit/牛纤连蛋白ELISA试剂盒

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