Canine BDNF ELISA Kit ELISA试剂盒,Canine BDNF ELISA Kit/犬BDNF ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Canine BDNF ELISA Kit ELISA试剂盒,Canine BDNF ELISA Kit/犬BDNF ELISA试剂盒

2024-10-24

Canine BDNF ELISA Kit/犬BDNF ELISA试剂盒

货号：EC1RB,EC1RBX5,EC1RBX10

规格：96 Tests,5X96 Tests,10X96 tests

价格：6641,29884,57271

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：其它

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	0.5 pg/mL
检测范围	0.41-100 pg/mL
样本类型/体积	血清 50 μL 血浆 50 μL 上清液 50 μL
操作时间	1 hr 20 min
测试时间	4 hr 45 min
Homogenous (no wash)	No
批间变异系数（CV）	<12%
批内变异系数（CV）	<10%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	5 x 96 Tests
组份	- 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	BDNF
Protein aliases	BDNF, BDNF precursor form, Brain-derived neurotrophic factor, ProBDNF
物种（Tested）	狗
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	BDNF
Gene ID	(Dog) 403461
UniProt ID	(Dog) Q7YRB4
Gene symbol	BDNF

Canine BDNF quantitates canine BDNF in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant canine BDNF.犬BDNF可定量测定血清，血浆，上清液中的犬BDNF。该检测试剂盒将只识别天然和重组犬BDNF。Target information 靶标信息BDNF (Brain-Derived Neurotrophic Factor) is a member of the neurotrophin family. BDNF is synthesized as pre-proBDNF, followed by cleavage to proBDNF. Although further processing generates the mature, 14 kDa protein, pro-BDNF is biologically active and is secreted in synaptic vesicles along with the mature form. BDNF is widely expressed in the central nervous system and acts in an autocrine and paracrine manner on several classes of neurons. Signaling occurs mainly through the tyrosine kinase receptor TrkB, although binding to the lower-affinity receptor, p75-NTR, has also been demonstrated. BDNF promotes neuronal survival and differentiation and has been shown to play a critical role in memory formation and synaptic regulation. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of BDNF is reduced in both Alzheimer's and Huntington disease patients, and may also play a role in the regulation of stress response and in the biology of mood disorders.BDNF（脑源性神经营养因子）是Neurotrophin家族的成员。 BDNF合成为pre-proBDNF，然后裂解为proBDNF。尽管进一步加工产生成熟的14 kDa蛋白，但pro-BDNF具有生物学活性，并与成熟形式一起分泌在突触小泡中。 BDNF在中枢神经系统中广泛表达，并以自分泌和旁分泌方式作用于几类神经元。信号主要通过酪氨酸激酶受体TrkB发生，尽管也已证明与低亲和力受体p75-NTR结合。 BDNF促进神经元存活和分化，并已被证明在记忆形成和突触调节中起关键作用。 BDNF由皮层神经元诱导，对于大脑中纹状体神经元的生存是必需的。 BDNF的表达在阿尔茨海默氏病和亨廷顿病患者中均降低，并且也可能在应激反应的调节和情绪障碍的生物学中起作用。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

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Canine BDNF ELISA Kit ELISA试剂盒,Canine BDNF ELISA Kit/犬BDNF ELISA试剂盒

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