JMJD2C Polyclonal Antibody

货号：PA5-23065

规格：100 µL

价格：5930

产品类型：标签抗体

品牌：Thermo Fisher

抗原：A synthetic peptide made to an internal region of

物种：人/小鼠

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	一抗	同型对照：
浓度：	0.5 mg/mL	用法：	1:100（ICC）；1:100（IF）；1:100（IHC(P)）；1:10000(WB)

产品详细信息Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.靶标信息Jumonji domain-containing protein 2C (JMJD2C)/ Lysine-specific demethylase 4C (KDM4C) is a histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3; thereby, playing a central role in histone code. KDM4C does not demethylate histone H3 'Lys-4', H3 'Lys-27', or H4 'Lys-20'. It demethylates trimethylated H3 "Lys-9' and H3 "Lys-36' residues. There is no activity on mono- or dimethylated residues. Demethylation of Lys residues generates formaldehyde and succinate.

数据：

JMJD2C Antibody (PA5-23065) in IFImmunofluorescent analysis of JMJD2C using a polyclonal antibody (Product # PA5-23065). JMJD2C Antibody (PA5-23065) in IHCImmunohistochemical analysis of JMJD2C using a polyclonal antibody (Product # PA5-23065). JMJD2C Antibody (PA5-23065) in WBWestern blot analysis of JMJD2C using a polyclonal antibody (Product # PA5-23065).

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