JMJD2C Monoclonal Antibody (OTI5B9)

货号：MA5-24956

规格：100 µL

价格：5956

产品类型：标签抗体

品牌：Thermo Fisher

抗原：Full-length protein expressed in 293T cell transfe

物种：人

宿主：小鼠

抗体亚型：IgG1, kappa

克隆号：OTI5B9

荧光染料：其它

类型:	一抗	同型对照：
浓度：	1 mg/mL	用法：	1:100（ICC）；1:100（IF）；1:50（IHC(P)）；1:2000(WB)

产品详细信息Jumonji domain-containing protein 2C (JMJD2C)/ Lysine-specific demethylase 4C (KDM4C) is a histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3; thereby, playing a central role in histone code. KDM4C does not demethylate histone H3 'Lys-4', H3 'Lys-27', or H4 'Lys-20'. It demethylates trimethylated H3 "Lys-9' and H3 "Lys-36' residues. There is no activity on mono- or dimethylated residues. Demethylation of Lys residues generates formaldehyde and succinate.

数据：

JMJD2C Antibody (MA5-24956) in ICC Immunofluorescent analysis of KDM4C in COS7 cells. Cells were transfected with a plasmid overexpressing KDM4C and probed with a KDM4C monoclonal antibody (Product # MA5-24956). JMJD2C Antibody (MA5-24956) in IHC (P)Immunohistochemistry was performed on paraffin-embedded ovary tissue. To expose target proteins, 10mM citric buffer, pH6.0, 100°C for 10min was used. Following antigen retrieval, tissues were probed with a KDM4C monoclonal antibody (Product # MA5-24956) at a dilution of 1:50. JMJD2C Antibody (MA5-24956) in WBWestern blot analysis of KDM4C in HEK293T cells in untransfected (Left lane) and transfected (Right lane) samples using 5 µg per lane. The samples were separated by SDS-PAGE and probed with KDM4C (Product # MA5-24956) monoclonal antibody.

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