Mouse FAS/TNFRSF6/Apo-1 ELISA Kit ELISA试剂盒,Mouse FAS/TNFRSF6/Apo-1 ELISA Kit/小鼠FAS / TNFRSF6 / Apo-1 ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Mouse FAS/TNFRSF6/Apo-1 ELISA Kit ELISA试剂盒,Mouse FAS/TNFRSF6/Apo-1 ELISA Kit/小鼠FAS / TNFRSF6 / Apo-1 ELISA试剂盒

2024-10-24

Mouse FAS/TNFRSF6/Apo-1 ELISA Kit/小鼠FAS / TNFRSF6 / Apo-1 ELISA试剂盒

货号：EM30RB,EM30RBX5,EM30RBX10

规格：96 Tests,5X96 Tests,10X96 tests

价格：6641,29884,57271

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：小鼠

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	8.2 pg/mL
检测范围	8.2-2,000 pg/mL
样本类型/体积	血清 50 μL 血浆 50 μL 上清液 50 μL
操作时间	1 hr 20 min
测试时间	4 hr 45 min
Homogenous (no wash)	No
批间变异系数（CV）	<12%
批内变异系数（CV）	<10%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	5 x 96 Tests
组份	- 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	FAS (CD95)
Protein aliases	Apo-1 antigen, Apoptosis-mediating surface antigen FAS, CD95, Fas (TNF receptor superfamily member), Fas antigen, FASLG receptor, lymphoproliferation, Tumor necrosis factor receptor superfamily member 6
物种（Tested）	小鼠
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	AI196731, APO1, APT1, CD95, Fas, lpr, TNFR6, Tnfrsf6
Gene ID	(Mouse) 14102
Gene symbol	Fas
UniProt ID	(Mouse) P25446

Mouse FAS/TNFRSF6/Apo-1 quantitates mouse FAS/TNFRSF6/Apo-1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse FAS/TNFRSF6/Apo-1.小鼠FAS / TNFRSF6 / Apo-1定量分析血清，血浆，上清液中的小鼠FAS / TNFRSF6 / Apo-1。该检测试剂盒将专门识别天然和重组小鼠FAS / TNFRSF6 / Apo-1。Target information 靶标信息FAS (Fas, CD95, APO-1) is a 46 kDa transmembrane glycoprotein that functions as a cell death receptor of the TNFR (tumor necrosis factor receptor) superfamily. FAS also exists in a soluble form that weight approximately 26kDa. Stimulation of FAS results in aggregation of its intracellular FAS-associated death domains (FADD), formation of the death-inducing signaling complex (DISC) and activation of caspases. The auto-proteolytic processing of the caspases in the complex trigger a downstream cascade that leads to apoptosis. FAS has been shown to activate NF-kappaB, MAPK3/ERK1, MAPK8/JNK, and is involved in transducing the proliferating signals in normal diploid fibroblast and T cells. At least eight alternatively spliced transcript variants encoding seven distinct isoforms have been described. The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full-length isoform. The Fas/Fas ligand system has been shown to play a role in a number of human diseases such as AIDS, hepatitis and cancer. It is also assumed that induction of apoptosis through FAS ligand pathway is predominantly involved in anti-viral immune responses.FAS（Fas，CD95，APO-1）是一种46 kDa的跨膜糖蛋白，起TNFR（肿瘤坏死因子受体）超家族的细胞死亡受体的作用。 FAS还以重量约26kDa的可溶形式存在。刺激FAS导致其细胞内FAS相关死亡域（FADD）聚集，诱导死亡的信号传导复合物（DISC）形成和胱天蛋白酶激活。复合物中半胱氨酸蛋白酶的自动蛋白水解过程触发下游级联反应，导致细胞凋亡。 FAS已被证明可以激活NF-κB，MAPK3 / ERK1，MAPK8 / JNK，并参与正常二倍体成纤维细胞和T细胞中增殖信号的转导。已经描述了编码八个不同同工型的至少八个选择性剪接的转录变体。缺乏跨膜结构域的同工型可能负调控由全长同工型介导的细胞凋亡。 Fas / Fas配体系统已显示出在许多人类疾病（如艾滋病，肝炎和癌症）中的作用。还假设通过FAS配体途径诱导细胞凋亡主要参与抗病毒免疫反应。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

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Mouse FAS/TNFRSF6/Apo-1 ELISA Kit ELISA试剂盒,Mouse FAS/TNFRSF6/Apo-1 ELISA Kit/小鼠FAS / TNFRSF6 / Apo-1 ELISA试剂盒

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