组蛋白甲基化修饰,H3K4,单克隆抗体,ING5 Recombinant Rabbit Monoclonal Antibody (119)

2024-10-24

ING5 Recombinant Rabbit Monoclonal Antibody (119)

货号:MA5-29370

规格:100 µL

价格:2746

产品类型:标签抗体

品牌:Thermo Fisher

抗原:Recombinant Human ING5 Protein

物种:人

宿主:兔

抗体亚型:IgG

克隆号:119

荧光染料:其它

类型:一抗同型对照:
浓度: 1mg/mL用法:1:5000-1:10000(ELISA);1-4 µL/mg of lysate(IP);1:500-1:2000(WB)
产品详细信息This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.This antibody has specificity for Human ING5.靶标信息ING5 is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway.
数据:

ING5 Antibody (MA5-29370) in WBWestern blot analysis of ING5 in Lane A: HepG2 Whole Cell Lysate (30 µg). Samples were probed using a ING5 Monoclonal Antibody (Product # MA5-29370) at a 1:500 dilution, followed by a Goat Anti-Rabbit IgG (H+L), Dylight 800 Secondary Antibody at a 1:10000 dilution. Western blot was performed under reducing conditions. Predicted band size:28 kDa. Observed band size:34 kDa.
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