组蛋白乙酰化修饰,H3K9,多克隆抗体,BRD4 Polyclonal Antibody

2024-10-24

BRD4 Polyclonal Antibody

货号:PA5-82519

规格:100 µL

价格:6049

产品类型:标签抗体

品牌:Thermo Fisher

抗原:Recombinant protein corresponding to Human BRD4

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:其它

类型:一抗同型对照:
浓度: 0.2mg/mL用法:0.25-2 µg/mL(ICC);0.25-2 µg/mL(IF);1:500-1:1,000(IHC(P))
产品详细信息Immunogen sequence: PQPAKPQQVI QHHHSPRHHK SDPYSTGHLR EAPSPLMIHS PQMSQFQSLT HQSPPQQNVQ PKKQELRAAS VVQPQPLVVV KEEKIHSPII RSEPFSPSLR PEPPKHPESI KAPVHLPQRP EMKPVDVGRP VIRPPEQNAP PP靶标信息BRD4, a ubiquitously expressed nuclear phosphoprotein, is a member of BET protein family. It is a human homolog of mouse MCAP and consists of 2 N-terminal bromodomains, a central ET-domain, and several kinase-like motifs in its N-terminus. It is expressed as 2 isoforms; the longer variant has a C-terminus region with a praline and glutamine-rich domains. BRD4 is a chromatin-binding protein whose expression is induced in response to growth stimuli. BRD4 acts at different stages of the cell cycleby interacting with proteins including RFC and SPA-1 and regulates cell growth. It also has a role in regulating chromosomal dynamics during mitosis. BRD4 functions as a cellular target for E2 protein of papillomavirus.
数据:

BRD4 Antibody (PA5-82519) in IFImmunofluorescent analysis of BRD4 in U-251 MG cells using a BRD4 polyclonal antibody (Product # PA5-82519). The analysis shows localization to nucleoplasm.

BRD4 Antibody (PA5-82519) in IHCImmunohistochemical analysis of BRD4 in human placenta using a BRD4 polyclonal antibody (Product # PA5-82519). The analysis shows high expression
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