Rabbit MIP-1beta ELISA Kit ELISA试剂盒,Rabbit MIP-1beta ELISA Kit/兔MIP-1beta ELISA试剂盒-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rabbit MIP-1beta ELISA Kit ELISA试剂盒,Rabbit MIP-1beta ELISA Kit/兔MIP-1beta ELISA试剂盒

2024-10-24

Rabbit MIP-1beta ELISA Kit/兔MIP-1beta ELISA试剂盒

货号：ER12RB,ER12RBX5

规格：96 Tests,5X96 Tests

价格：6641,29884

产品类型：Platinum ELISA

品牌：Thermo Fisher

物种：兔

宿主：其它

抗体亚型：其它

荧光染料：其它

灵敏度	24.6 pg/mL
检测范围	24.6-6,000 pg/mL
样本类型/体积	血清 50 μL 血浆 50 μL 上清液 50 μL
操作时间	1 hr 20 min
测试时间	4 hr 45 min
Homogenous (no wash)	No
批间变异系数（CV）	<12%
批内变异系数（CV）	<10%
仪器设备	Colorimetric Microplate Reader 酶标仪
规格	5 x 96 Tests
组份	- 预包被96孔板 - 标准品 - 测定稀释浓缩液 - 生物素化检测抗体 - SAV-HRP - 洗涤液 - 显色剂 - 终止液 - 胶板盖
储存温度	2-8℃
Protein name	CCL4
Protein aliases	ACT-2, C-C motif chemokine 4, immune activation gene 2, Immune activation protein 2, Macrophage inflammatory protein 1-beta, MIP-1-beta, Small-inducible cytokine A4
物种（Tested）	兔
试剂盒类型	Sandwich ELISA Kit
标记（染料）	HRP
检测抗体偶联物	Biotin
Gene aliases	ACT2, CCL4, SCYA4
Gene ID	(Rabbit) 100008984
Gene symbol	CCL4
UniProt ID	(Rabbit) P46632

Rabbit MIP-1beta quantitates rabbit MIP-1beta in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rabbit MIP-1beta.兔MIP-1beta定量测定血清，血浆，上清液中的兔MIP-1beta。该检测试剂盒将专门识别天然和重组兔MIP-1beta。Target information 靶标信息CCL4 (macrophage inflammatory protein 1-beta, MIP1B) belongs to the intercrine beta (chemokine CC) family. Functionally, CCL4 is involved in chemotactic and proinflammatory effects, and homeostasis. CCL4 is produced by macrophages upon stimulation by bacterial endotoxins. CCL4 recruits and stimulates various inflammatory cells at sites of inflammation. CCL4 is produced by lymphocytes, macrophages and dendritic cells. Both CCL4 and the related protein CCL3 participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells. While both CCL4 and CCL3 exert similar effects on monocytes, their effect on lymphocytes differ, with CCL4 selectively attracting CD4+ lymphocytes and CCL3 selectively attracting CD8+ lymphocytes. Additionally, both have been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. The processed form of CCL4 can induce down-modulation of surface expression of the chemokine receptor CCR5, thus inhibiting the CCR5-mediated entry of HIV-1 in T cells. CCL4 binds with high affinity to CCR5 receptors.CCL4（巨噬细胞炎性蛋白1-beta，MIP1B）属于分泌间beta（趋化因子CC）家族。在功能上，CCL4参与趋化和促炎作用以及体内稳态。细菌内毒素刺激巨噬细胞产生CCL4。 CCL4在炎症部位募集并刺激各种炎症细胞。 CCL4由淋巴细胞，巨噬细胞和树突状细胞产生。 CCL4和相关蛋白CCL3均通过调节炎性细胞所选亚组的运输和激活状态，参与宿主对入侵的细菌，病毒，寄生虫和真菌病原体的反应。尽管CCL4和CCL3对单核细胞的作用相似，但它们对淋巴细胞的作用却有所不同，CCL4选择性吸引CD4 +淋巴细胞，而CCL3选择性吸引CD8 +淋巴细胞。另外，已显示两者都是对B细胞，嗜酸性粒细胞和树突状细胞的有效趋化剂。 CCL4的加工形式可以诱导趋化因子受体CCR5的表面表达下调，从而抑制TCR中的CCR5介导的HIV-1进入。 CCL4以高亲和力与CCR5受体结合。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。不用于诊断过程。未经明确授权不得转售。

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Rabbit MIP-1beta ELISA Kit ELISA试剂盒,Rabbit MIP-1beta ELISA Kit/兔MIP-1beta ELISA试剂盒

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