Rabbit IL-8 ELISA Kit ELISA试剂盒,Rabbit IL-8 ELISA Kit/兔IL-8 ELISA试剂盒

2024-10-24

Rabbit IL-8 ELISA Kit/兔IL-8 ELISA试剂盒

货号:ER10RB,ER10RBX5

规格:96 Tests,5X96 Tests

价格:6641,29884

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:兔

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.8 pg/mL

检测范围0.8-200 pg/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameIL-8
Protein aliasesC-X-C motif chemokine 8, Chemokine (C-X-C motif) ligand 8, IL-8, Interleukin-8, NAP-1, Neutrophil attractant/activation protein 1, neutrophil attractant/activation protein-1, Permeability factor 1, PF1, RPF1

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesCXCL8, IL8
Gene ID(Rabbit) 100009129
Gene symbolIL8
UniProt ID(Rabbit) P19874
Rabbit IL-8 quantitates rabbit IL-8 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rabbit IL-8.兔IL-8定量测定血清,血浆,上清液中的兔IL-8。该检测试剂盒将专门识别天然和重组兔IL-8。Target information 靶标信息Interleukin 8 (IL-8, CXCL8) is a 72 amino acid pro-inflammatory factor which belongs to the CXC subfamily of chemokines, and are bound by the cell surface receptors IL-8RA and IL-8RB. IL-8 functions as a chemoattractant and potent angiogenic factor. The expression and secretion of IL-8 can be induced by diverse inflammatory stimuli in many cells, including macrophages and endothelial cells. In endothelial cells, IL-8 is present in storage vesicles called Weibel-Palade bodies. IL-8, first isolated from osteosarcoma cells, contains the ELR-motif (N-terminal Glu-Leu-Arg amino acid sequence) and signals through the CXCR1 and CXCR2 receptors. Previous nomenclature for IL-8 includes neutrophil activating protein 1 (NAP-1), granulocyte chemotactic protein 1 (GCP-1), monocyte-derived neutrophil-activating peptide (MONAP) and protein 3-10C. IL-8 and ten other members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. Cancer studies have demonstrated a role for IL-8 in the angiogenesis and growth of tumours, and IL-8 is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection.白介素8(IL-8,CXCL8)是一种72个氨基酸的促炎因子,属于趋化因子的CXC亚家族,并与细胞表面受体IL-8RA和IL-8RB结合。 IL-8用作化学吸引剂和有效的血管生成因子。 IL-8的表达和分泌可通过多种细胞(包括巨噬细胞和内皮细胞)中的多种炎症刺激来诱导。在内皮细胞中,IL-8存在于称为Weibel-Palade体的储泡中。首先从骨肉瘤细胞中分离出来的IL-8含有ELR-基序(N端Glu-Leu-Arg氨基酸序列),并通过CXCR1和CXCR2受体发出信号。 IL-8的先前命名法包括嗜中性粒细胞激活蛋白1(NAP-1),粒细胞趋化蛋白1(GCP-1),单核细胞衍生的嗜中性粒细胞激活肽(MONAP)和蛋白3-10C。 IL-8和CXC趋化因子基因家族的其他十个成员在映射到染色体4q的区域中形成趋化因子基因簇。癌症研究表明IL-8在肿瘤的血管生成和生长中起作用,据信IL-8在毛细支气管炎(一种由病毒感染引起的常见呼吸道疾病)的发病机理中起作用。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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