Mouse CD80 ELISA Kit ELISA试剂盒,Mouse CD80 ELISA Kit/小鼠CD80 ELISA试剂盒

2024-10-24

Mouse CD80 ELISA Kit/小鼠CD80 ELISA试剂盒

货号:EM16RB,EM16RBX5,EM16RBX10

规格:96 Tests,5X96 Tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:小鼠

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

28 pg/mL

检测范围28-7,000 pg/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameCD80 (B7-1)
Protein aliasesActivation B7-1 antigen, B7, B7 protein, CD80, T-lymphocyte activation antigen CD80

物种(Tested)

小鼠

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesB7, B71, Cd28l, Cd80, Ly-53, Ly53, MIC17, TSA1
Gene ID(Mouse) 12519
Gene symbolCd80
UniProt ID(Mouse) Q00609
Mouse CD80 quantitates mouse CD80 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse CD80.小鼠CD80定量分析血清,血浆,上清液中的小鼠CD80。 该检测试剂盒将专门识别天然和重组小鼠CD80。Target information 靶标信息CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28, and of an inhibitory receptor CTLA-4 (CD152). Both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, and both molecules can also substitute for each other in this process. CD80 is rapidly induced on the surface of in vitro activated B cells, with Epstein Barr Virus (EBV) transformed B cell lines, with Burkitts lymphoma cell lines, with freshly isolated follicular B lymphoma cells, T cells, and monocytes. The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 and CTLA4 ligands of T cells. Diseases associated with CD80 dysfunction include gallbladder squamous cell carcinoma and myocarditis.CD80(B7-1)和CD86(B7-2)是T细胞关键共刺激分子CD28和抑制受体CTLA-4(CD152)的配体。 两个B7分子均在专业抗原呈递细胞上表达,并且对于T细胞活化至关重要,并且在此过程中,两个分子也可以彼此替代。 CD80可通过爱泼斯坦巴尔病毒(EBV)转化的B细胞系,伯基兹淋巴瘤细胞系,新鲜分离的滤泡性B淋巴瘤细胞,T细胞和单核细胞在体外活化的B细胞表面快速诱导。 由于与T细胞的CD28和CTLA4配体结合,B淋巴细胞活化抗原B7-1为T淋巴细胞提供了调节信号。 与CD80功能障碍有关的疾病包括胆囊鳞状细胞癌和心肌炎。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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